GvHD Connect
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Chronic Graft-Versus-Host Disease Is Characterized by High Levels and Distinctive Tissue-of-Origin Patterns of Cell-Free DNA

Chronic Graft-Versus-Host Disease Is Characterized by High Levels and Distinctive Tissue-of-Origin Patterns of Cell-Free DNA

Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651673/

Chronic graft-versus-host disease (cGvHD) is a devastating complication of hematopoietic stem cell transplantation (HSCT). Effective early detection may improve the outcome of cGvHD.

Chronic graft-versus-host disease (cGvHD) had unique cfDNA signatures, and CfDNA patterns are potentially useful biomarkers for cGvHD.

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BMQI is a relevant, simple, timely, and inexpensive quality indicator in the context of G-CSF-primed BM. Poorer quality of marrow collection may contribute to an increased risk of aGVHD.

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Unconventional T cells with restricted TCR repertoire have shown favorable antitumor potency with near zero incidence of GvHD.

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Genital Graft Versus Host Disease in Children – an Underdiagnosed and Undertreated Entity

Genital Graft Versus Host Disease in Children – an Underdiagnosed and Undertreated Entity

Source : https://pubmed.ncbi.nlm.nih.gov/37926190/

Our case series highlights the significant association between chronic oral and genital GVHD. It is imperative to examine the genital area in all children on follow up for chronic GVHD...

It is imperative to examine the genital area in all children on follow-up for chronic GVHD, because the association between mouth and genital GVHD rate is high and undertreated in children.

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Oral Chronic Graft-Versus-Host Disease in Post-Hematopoietic Stem Cell Transplant Patients Following SARS-CoV-2 Vaccination: Case Reports

Oral Chronic Graft-Versus-Host Disease in Post-Hematopoietic Stem Cell Transplant Patients Following SARS-CoV-2 Vaccination: Case Reports

Source : https://karger.com/cro/article/16/1/1287/869328/Oral-Chronic-Graft-versus-Host-Disease-in-Post

Abstract. Patients receiving allogeneic hematopoietic stem cell transplant may experience graft-versus-host disease (GVHD) in which donor immune cells cause an immune reaction in host tissues. Severe acute respiratory syndrome coronavirus-2...

Patients must be counseled on risks when they receive any vaccine, and HCPs managing patients with GVHD must be aware of the potential to stimulate oral GVHD.