Comprehensive Perspective for Lung Cancer Characterisation Based on AI Solutions Using CT Images

Source : https://www.mdpi.com/2077-0383/10/1/118

Lung cancer is still the leading cause of cancer death in the world. For this reason, novel approaches for early and more accurate diagnosis are needed. Computer-aided decision (CAD) can...

KRAS G12V mutation upregulates PD‐L1 expression via TGF‐β/EMT signaling pathway in human non‐small‐cell lung cancer

Source : https://onlinelibrary.wiley.com/doi/abs/10.1002/cbin.11524

Although clinical data suggest remarkable promise for targeting programmed cell death protein‐1 (PD‐1) and ligand (PD‐L1) signaling in non‐small‐cell lung cancer (NSCLC), it is still largely undeterm...

Exquisitely Specific anti-KRAS Biodegraders Inform on the Cellular Prevalence of Nucleotide-Loaded States

Source : https://pubs.acs.org/doi/full/10.1021/acscentsci.0c01337

Mutations to RAS proteins (H-, N-, and K-RAS) are among the most common oncogenic drivers, and tumors harboring these lesions are some of the most difficult to treat. Although covalent...