Allogeneic Stem Cell Transplantation in Patients with High-Risk Multiple Myeloma: Utopia or Continuous Challenge in Aiming for Cure? - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34110512/

Nowadays, several novel agents have been introduced in the treatment of multiple myeloma, not only resulting in high response rates and prolonged survival but also offering good quality of life....

Multiple Myeloma: From Baby Steps to Giant Strides

Source : https://ascopubs.org/doi/10.1200/OP.21.00327

The past three decades have witnessed major paradigm shifts in the management of multiple myeloma (MM), resulting in significant improvements not only in the survival from the diagnosis but also...

Immunotherapy in Multiple Myeloma-Time for a Second Major Paradigm Shift

Source : https://ascopubs.org/doi/full/10.1200/OP.21.00032

Multiple myeloma (MM) is a genetically heterogenous disease and remains mostly incurable with a small group of patients achieving long-term disease remission. The past decade witnessed enormous efforts to break...

Evolving Paradigms of Therapy for Multiple Myeloma: State of the Art and Future Directions - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34110937/

This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable....

Inhibition of Pim-2 kinase by LT-171-861 promotes DNA damage and exhibits enhanced lethal effects with PARP Inhibitor in multiple myeloma - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34111425/

Multiple myeloma (MM) is a malignancy of antibody-producing plasma cells with genomic instability and genetic abnormality as its two hallmarks. Therefore, DNA damage is pervasive in MM cells, which indicates...