Extreme Hypofractionation with SBRT in Localized Prostate Cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34436023/
Prostate cancer is the most commonly diagnosed cancer among men around the world. Radiotherapy is a standard of care treatment option for men with localized prostate cancer. Over the years,...
Salvage Radical Prostatectomy for Radio-Recurrent Prostate Cancer: An Updated Systematic Review of Oncologic, Histopathologic and Functional Outcomes and Predictors of Good Response - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34436018/
A valid treatment option for recurrence after definite radiotherapy (RT) for localized prostate cancer (PC) is salvage radical prostatectomy (SRP). However, data on SRP are scarce, possibly resulting in an...
Vitamin D and the risk for cancer: a molecular analysis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34411566/
Uncontrolled overgrowth of cells, such as in cancer, is an unavoidable risk in life that affects nearly every second individual in industrialized countries. However, in part this risk can be...
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Naveed Saleh, MD, MS – Skipta Team4yrKey Points • Conclusion/Relevance: “Rapidly growing cells of the immune system as well as those of malignant tumors rely on comparable genes and pathways, some of which are modulated by vitamin Show More
Methylseleninic acid overcomes programmed death-ligand 1-mediated resistance of prostate cancer and lung cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34411338/
Programmed death-ligand 1 (PD-L1)-mediated resistance has become a great challenge for tumor treatment. Cisplatin increased tumor PD-L1 expression, promoted chemotherapy resistance. Interferon-γ (IFN-γ)-induced PD-L1 expression might facilitate immunotherapy resistance. Methylseleninic...
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Naveed Saleh, MD, MS – Skipta Team4yrKey Points • Conclusion/Relevance: “Our findings, for the first time, demonstrated that MSeA is a potential agent to overcome PD-L1-mediated chemotherapy and immunotherapy resistance. Such information might have potential clinical implications for Show More
Factors Associated With Discontinuation of Active Surveillance among Men With Low-Risk Prostate Cancer: A Population-Based Study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34412510/
Although the uptake of AS significantly increased over time, there has been a relatively high rate of discontinuation over 5 years. Factors associated with transition to definitive treatment were younger...