micro-community-banner
 
  • Saved

1yr

Did you know?  Gene therapy has seen unprecedented growth, with over 1,000 clinical trials currently underway. Recent successes include FDA approval of therapies that correct genetic disorders like spinal muscular atrophy, offering potentially curative treatments for conditions once deemed untreatable.

How close are we to making gene therapy a standard option in clinical practice, and what challenges remain?

background

How close are we to making gene therapy a standard option in clinical practice, and what challenges remain?

  • Saved

1yr
Advances in PSMA Alpha Theragnostics

Advances in PSMA Alpha Theragnostics

Source : https://pubmed.ncbi.nlm.nih.gov/38658300/

Alpha theranostics offer an attractive alternative form of therapy, which has best been investigated and documented with 225 Ac-PSMA in patients with prostate cancer. Advantages offered by targeted alpha therapy...

Alpha theranostics with 225Ac-PSMA in prostate cancer show promising efficacy, with improved outcomes and acceptable side effects, though optimal patient selection, dosing, and side effect management remain unresolved.

  • Saved

1yr
Radiation Therapy Technology Advances and Mitigation of Subsequent Neoplasms in Childhood Cancer Survivors

Radiation Therapy Technology Advances and Mitigation of Subsequent Neoplasms in Childhood Cancer Survivors

Source : https://pubmed.ncbi.nlm.nih.gov/38430101/

Future cancer care is expected to involve several available RT technologies, necessitating evidence and strategies to assess the performance of competing treatments. It is essential to maximize the utilization of...

The paper reviews challenges and opportunities in assessing subsequent neoplasms from radiation therapy in pediatric cancer patients, highlighting knowledge gaps and the need for improved data collection and follow-up.

  • Saved

1yr
Radiation therapy with phenotypic medicine: towards N-of-1 personalization

Radiation therapy with phenotypic medicine: towards N-of-1 personalization

Source : https://pubmed.ncbi.nlm.nih.gov/38514762/

In current clinical practice, radiotherapy (RT) is prescribed as a pre-determined total dose divided over daily doses (fractions) given over several weeks. The treatment response is typically assessed months after...

Artificial intelligence-driven phenotypic medicine offers a novel approach to personalize radiotherapy, potentially optimizing dose selection and adaptation in real-time to improve treatment outcomes.

  • Saved

1yr
Radiation Therapy for Sister Mary Joseph's Nodule: A Review

Radiation Therapy for Sister Mary Joseph's Nodule: A Review

Source : https://pubmed.ncbi.nlm.nih.gov/38405321/

Umbilical metastasis, known as SMJN, is a rare disease and is divided into 4 types based on the location of the disease and extent mechanism. Although the prognosis of the...

Umbilical metastasis (SMJN) has a poor prognosis, but some patients survive over 2 years. Limited data suggests both short and high-dose radiation therapy may offer benefits.