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3yr
Lung cancer presenting with central nervous system metastasis: Clinicopathological and molecular analysis of 171 cases

Lung cancer presenting with central nervous system metastasis: Clinicopathological and molecular analysis of 171 cases

Source : https://www.sciencedirect.com/science/article/abs/pii/S1092913422001848?via=ihub

A subset of lung carcinoma presents initially with brain metastasis. Precise subtyping is mandatory for optimized treatment of these advanced aggressive carcinomas. We herein analyzed surgical biopsies from 171 Patients...


Conclusions: This study highlights a highly heterogeneous molecular background in lung cancer presenting with CNS metastases. These findings highlight the need for individualized tumor testing strategies looking for potential therapeutic targets for this aggressive disease.


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3yr
Modeling Costs and Life-Years Gained by Population-Wide Next-Generation Sequencing or Single-Gene Testing in Nonsquamous Non-Small-Cell Lung Cancer in the United States - PubMed

Modeling Costs and Life-Years Gained by Population-Wide Next-Generation Sequencing or Single-Gene Testing in Nonsquamous Non-Small-Cell Lung Cancer in the United States - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/36634300/

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Conclusions: On the basis of current evidence, population-level simulations demonstrate that clinically relevant gains in survival with non-negligible reduction in costs are obtainable from widespread adoption of NGS testing and appropriate treatment matching for patients with advanced nonsquamous non–small-cell lung cancer.


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3yr
Highlights from the American Society of Clinical Oncology Gastrointestinal Cancers Symposium

The 2023 ASCO Gastrointestinal Cancers Symposium marked its 20th year with presentations, abstracts, and posters highlighting the latest innovations in treating anal, colorectal, esophageal, stomach, hepatobiliary, pancreatic, and other types of gastrointestinal cancers.

Click above to access a summary of what's happening so far in the conference this year.

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3yr
A Preview of the 2023 American Society of Clinical Oncology Gastrointestinal Cancers Symposium

The American Society of Clinical Oncology (ASCO) Gastrointestinal (GI) Cancers Symposium is being held Jan. 19 to 21, 2023, in San Francisco. The event is being held in person and online, with online-only access also available.

Click above to access a summary of program highlights that caught the attention of our team of analysts.

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3yr
Robust Performance of the Novel Research-Use-Only Idylla GeneFusion Assay Using a Diverse Set of Pathological Samples with a Proposed 1-Day Workflow for Advanced NSCLC Evaluation - PubMed

Robust Performance of the Novel Research-Use-Only Idylla GeneFusion Assay Using a Diverse Set of Pathological Samples with a Proposed 1-Day Workflow for Advanced NSCLC Evaluation - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/36612287/

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Conclusions: Our results suggest that the Idylla GeneFusion assay is a reliable tool to define gene fusion status and may be a valuable stand-alone diagnostic test when time efficiency is needed or NGS is not feasible.