Association between the patients' symptom burden and their family caregivers' benefit finding in non-small cell lung cancer receiving combined chemotherapy - Supportive Care in Cancer
Source : https://link.springer.com/article/10.1007/s00520-023-07590-0
Purpose The aim of the study is to explore the relationship between the patients' symptom burden and their family caregivers' benefit finding in non-small cell lung cancer (NSCLC) receiving combined...
Conclusions: The symptom burden of patients is adversely correlated with the benefit finding of family caregivers in NSCLC receiving combined chemotherapy; the lighter the symptom burden of patients, the higher the benefit finding of family caregivers. Therefore, appropriate nursing measures should be taken for fatigue, lack of appetite, and...
The significance of the crosstalk between ubiquitination or deubiquitination and ncRNAs in non-small cell lung cancer
Source : https://www.frontiersin.org/articles/10.3389/fonc.2022.969032/full
Lung cancer (LC) remains the leading cause of cancer-related deaths worldwide, with extremely high morbidity and mortality rates. Non-small cell lung cancer (NSCLC) is the most critical type of LC....
Conclusions: This review presents several typical examples of the important effects of ncRNAs and ubiquitination (or deubiquitination) in NSCLC, aiming to provide more creative ideas for exploring the diagnosis and treatment of NSCLC.
Ultrafast Gene Fusion Assessment for Nonsquamous NSCLC - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36718140/
UFGFA using NGS and reverse-transcriptase polymerase chain reaction approaches had an equal level of detection of gene fusion but with some technique-specific limitations. Nevertheless, UFGFA detection in routine clinical care...
Conclusions: UFGFA using NGS and reverse-transcriptase polymerase chain reaction approaches had an equal level of detection of gene fusion but with some technique-specific limitations. Nevertheless, UFGFA detection in routine clinical care is feasible with both systems allowing faster initiation of therapy and a broad degree of screening.
Ascites During Selpercatinib Treatment: Need for a Multidisciplinary Approach - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36682848/
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Conclusions: The brief report by Kalchiem-Dekel et al. 1 interestingly described the occurrence of spontaneous chylous effusions in patients who underwent treatment with multiple tyrosine kinase inhibitors and specific RET inhibitors.
Cip2a induces arginine biosynthesis and promotes tumor progression in non-small cell lung cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36705466/
Cancerous inhibitor of protein phosphatase 2A (Cip2a) is an oncoprotein, playing important roles in tumor progression. However, the underlying mechanisms by which Cip2a promotes tumor aggressiveness in NSCLC remain to...
Conclusions: Our findings provide new insights into the mechanisms of Cip2a in promoting tumor progression and suggest that Cip2a represents a potential therapeutic target for treating NSCLC.