Clinical progress of anti-angiogenic targeted therapy and combination therapy for gastric cancer
Source : https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1148131/full
The incidence of gastric cancer is increasing year by year. Most gastric cancers are already in the advanced stage with poor prognosis when diagnosed, which means the current treatment is...
Relevance: This review will serve as a good reference for the clinical research of anti-angiogenic targeted drugs in the treatment of gastric cancer.
Associations of subcutaneous fat area and Systemic Immune-inflammation Index with survival in patients with advanced gastric cancer receiving dual PD-1 and HER2 blockade - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37349127/
Pretreatment SFA and SII were significantly associated with OS in patients with advanced gastric cancer. A comprehensive analysis of SII and SFA may improve the prognostic stratification of patients with...
Conclusion: Pretreatment SFA and SII were significantly associated with OS in patients with advanced gastric cancer. A comprehensive analysis of SII and SFA may improve the prognostic stratification of patients with gastric cancer receiving dual PD-1 and HER2 blockade.
Ultrasensitive detection of gastric cancer biomarkers via a frequency shift-based SERS microfluidic chip
Source : https://pubs.rsc.org/en/content/articlelanding/2023/AN/D3AN00535F
Highly sensitive protein biomarker detection is critical for the diagnosis of gastric cancer (GC), however the accurate and sensitive detection of low-abundance proteins in early-stage GC is still a challenge....
Relevance: Herein, a surface-enhanced Raman scattering frequency shift assay was performed on a developed microfluidic chip for the detection of GC protein biomarkers carcinoembryonic antigen (CEA) and vascular endothelial growth factor (VEGF). T
The Journal of Minimally Invasive Surgery
Source : https://www.e-jmis.org/journal/view.html?doi=10.7602/jmis.2023.26.2.47
Jeong Ho Song, Sang-Yong Son, Sang-Uk Han. Journal of Minimally Invasive Surgery 2023;26:47-50. https://doi.org/10.7602/jmis.2023.26.2.47
Conclusions: Surgical oncologists play a pivotal role as essential members of multidisciplinary teams in the era of precision medicine. Additional roles, such as designing clinical trials and making guidelines, are required for current surgical oncologists. In the future, the activity field of surgical oncologists will be further...
Ramucirumab plus irinotecan / leucovorin / 5-FU versus ramucirumab plus paclitaxel in patients with advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction, who failed one prior line of palliative chemotherapy - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37337155/
NCT03081143 Date of registration: 13.11.2015.
Discussion: The already completed RAMIRIS phase II demonstrated feasibility and efficacy of FOLFIRI-Ram. Especially docetaxel-pretreated patients seemed to markedly benefit from FOLFIRI-Ram, with favorable response- and PFS rates and lower toxicity. This offers a rationale for the phase III trial. If the RAMIRIS III trial transfers and...