Laparoscopic total gastrectomy for concurrent gastric cancer and complete agenesis of the dorsal pancreas - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36148900/
We present an unusual case of laparoscopic total gastrectomy with lymph node dissection in a 56-year-old woman with gastric cancer and agenesis of the dorsal pancreas (ADP). Esophagogastroduodenoscopy revealed erosive...
Conclusion: Laparoscopic surgery, with careful preoperative anatomic evaluation, can be considered for concurrent gastric cancer and ADP.
Dynamic Alteration in HLA-E Expression and Soluble HLA-E via Interaction with Natural Killer Cells in Gastric Cancer - Annals of Surgical Oncology
Source : https://link.springer.com/article/10.1245/s10434-022-12505-0
Background Some reports showed the immune tolerance of soluble human leukocyte antigen E (HLA-E), but the role that soluble HLA-E plays in gastric cancer (GC) is unknown. We aimed to...
Conclusions: HLA-E expression dynamically changes on GC cells and in conditioned medium. Furthermore, soluble HLA-E can contribute to immune escape in GC cell lines, which may have significance in clinical practice. Moreover, soluble HLA-E may be a potential prognostic biomarker.
Efficacy and Safety of FOLFOX in Advanced Gastric Cancer Initially Presenting With Disseminated Intravascular Coagulation - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36099124/
1 Third Department of Internal Medicine, University of Toyama, Toyama, Japan. 2 Third Department of Internal Medicine, University of Toyama, Toyama, Japan; [email protected]. 3 Department of Clinical Oncology, University of...
Conclusion: FOLFOX therapy is well tolerated and effective in patients with AGC initially presenting with DIC and subsequent second-line treatment might be crucial for better prognosis.
Family history of malignant tumor is a predictor of gastric cancer prognosis: Incorporation into a nomogram - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36107576/
The purpose of this study was to investigate the impact of a family history of malignant tumor on the prognosis of patients with gastric cancer and develop a nomogram that...
Conclusion/Relevance: The nomogram developed in this research can be used as an important tool to predict the prognosis of gastric cancer patients with family history data.
Tumor-infiltrating CD226+CD8+ T cells are associated with postoperative prognosis and adjuvant chemotherapeutic benefits in gastric cancer patients - Journal of Cancer Research and Clinical Oncology
Source : https://link.springer.com/article/10.1007/s00432-022-04346-x
Purpose Defining the phenotypic characteristics of CD8+ T cell subsets in gastric cancer (GC) can help remodel the immune microenvironment of the tumor, thereby improving patient prognosis. CD226 has recently...
Conclusion: CD226 CD8 T cells may represent a novel therapeutic target and a useful marker of prognosis and therapeutic response in patients with GC.