Molecular mechanisms underlying the action of carcinogens in gastric cancer with a glimpse into targeted therapy - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36149600/
In this review, we highlight recent clinical trial data reported in the literature dealing with different ways to target various carcinogens in gastric cancer. Moreover, we touch upon other multidisciplinary...
Conclusions: In this review, we highlight recent clinical trial data reported in the literature dealing with different ways to target various carcinogens in gastric cancer. Moreover, we touch upon other multidisciplinary therapeutic approaches such as surgery, adjuvant and neoadjuvant chemotherapy. Rational clinical trials focusing on...
Laparoscopic total gastrectomy for concurrent gastric cancer and complete agenesis of the dorsal pancreas - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36148900/
We present an unusual case of laparoscopic total gastrectomy with lymph node dissection in a 56-year-old woman with gastric cancer and agenesis of the dorsal pancreas (ADP). Esophagogastroduodenoscopy revealed erosive...
Conclusion: Laparoscopic surgery, with careful preoperative anatomic evaluation, can be considered for concurrent gastric cancer and ADP.
Dynamic Alteration in HLA-E Expression and Soluble HLA-E via Interaction with Natural Killer Cells in Gastric Cancer - Annals of Surgical Oncology
Source : https://link.springer.com/article/10.1245/s10434-022-12505-0
Background Some reports showed the immune tolerance of soluble human leukocyte antigen E (HLA-E), but the role that soluble HLA-E plays in gastric cancer (GC) is unknown. We aimed to...
Conclusions: HLA-E expression dynamically changes on GC cells and in conditioned medium. Furthermore, soluble HLA-E can contribute to immune escape in GC cell lines, which may have significance in clinical practice. Moreover, soluble HLA-E may be a potential prognostic biomarker.
Efficacy and Safety of FOLFOX in Advanced Gastric Cancer Initially Presenting With Disseminated Intravascular Coagulation - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36099124/
1 Third Department of Internal Medicine, University of Toyama, Toyama, Japan. 2 Third Department of Internal Medicine, University of Toyama, Toyama, Japan; [email protected]. 3 Department of Clinical Oncology, University of...
Conclusion: FOLFOX therapy is well tolerated and effective in patients with AGC initially presenting with DIC and subsequent second-line treatment might be crucial for better prognosis.
Family history of malignant tumor is a predictor of gastric cancer prognosis: Incorporation into a nomogram - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36107576/
The purpose of this study was to investigate the impact of a family history of malignant tumor on the prognosis of patients with gastric cancer and develop a nomogram that...
Conclusion/Relevance: The nomogram developed in this research can be used as an important tool to predict the prognosis of gastric cancer patients with family history data.