The Clinicopathological Features of Mixed Carcinoma in 7,215 Patients with Gastric Cancer in a Tertiary Hospital in South Korea - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36510778/
Mixed carcinoma was associated with lymph node metastasis compared to other histological GC subtypes. And it showed relatively common submucosal invasion in early GC, but the rates of venous invasion...
Conclusions: Mixed carcinoma was associated with lymph node metastasis compared to other histological GC subtypes. And it showed relatively common submucosal invasion in early GC, but the rates of venous invasion and distant metastasis were lower in advanced GC. Further research is needed to uncover the mechanism underlying these characteristics...
A liquid biopsy signature of circulating exosome-derived mRNAs, miRNAs and lncRNAs predict therapeutic efficacy to neoadjuvant chemotherapy in patients with advanced gastric cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36510184/
At present, there is no validated marker to identify the subpopulation of patients with advanced gastric cancer (AGC) who might benefit from neoadjuvant chemotherapy (NACT). In view of this clinical...
Conclusions: Numerous miRNAs, mRNAs and lncRNAs were identified to be associated with the response to NACT in patients with AGC, and it was validated in an independent cohort with promising AUC values. Furthermore, we established a 6-exosome-RNA panel that could robustly identified responders from non-responders treated with fluorouracil-based...
Sex-dependent associations between MAP3K1 gene polymorphisms and soy products with the gastric cancer risk in Korea: a case-control study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36510163/
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Conclusions: "Men with the risk allele of MAP3K1 had a significantly increased GC risk compared to GG homozygotes; this trend was more pronounced in those with low intake of soy products."
Therapeutic response to ramucirumab + folfiri in patients with metastatic gastric cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36505597/
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Conclusions: Ultimately, according to the obtained results, it may be concluded that the therapeutic response to ramucirumab folfiri in a patient with metastatic gastric cancer is good, and the use of this regimen is recommended."
Increased Expression of POSTN Predicts Poor Prognosis: a Potential Therapeutic Target for Gastric Cancer - Journal of Gastrointestinal Surgery
Source : https://link.springer.com/article/10.1007/s11605-022-05517-4
Background Periostin (POSTN) is involved in many biological processes and is associated with the occurrence and development of several cancers, while its role in gastric cancer is not clear. We...
Conclusions: POSTN plays an important role in the progression and prognosis of gastric cancer, and it may serve as a useful biomarker to predict survival in gastric cancer patients.