RNA-binding protein ENO1 promotes the tumor progression of gastric cancer by binding to and regulating gastric cancer-related genes - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37201055/
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Conclusions: ENO1 may play a role in GC by binding to and regulating GC-related genes. Our findings extend understandings of its mechanism as a clinical therapeutic target.
Pathological complete response with nivolumab for recurrence of liver metastasis after gastrectomy of gastric cancer - Surgical Case Reports
Source : https://surgicalcasereports.springeropen.com/articles/10.1186/s40792-023-01668-x
Background Advanced gastric cancer has an unfavorable prognosis and poor curability. Immune checkpoint inhibitors, such as nivolumab, have recently emerged as a potential solution for this aggressive disease. However, there...
Conclusion: Here, we report a case of recurrent gastric cancer with liver metastasis, where complete pathological response was achieved with nivolumab. PET–CT could aid in making treatment strategy decisions about the need for surgical intervention.
The Role of Angiogenesis Targeted Therapies in Metastatic Advanced Gastric Cancer: A Narrative Review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37176668/
Since bevacizumab was first approved by the U.S. Food and Drug Administration as an anti-angiogenic therapy in 2004, angiogenesis-targeted therapy has been developed for various types of solid tumors. To...
Relevance: This review offers an overview of the history of clinical trials focused on anti-angiogenic for patients with AGC and presents future perspectives in this area.
Initial Report of Second-Line FOLFIRI in Combination with Ramucirumab in Advanced Gastroesophageal Adenocarcinomas: A Multi-Institutional Retrospective Analysis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/30470690/
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Conclusion: We provide the first data suggesting FOLFIRI-ram is a safe, non-neurotoxic regimen comparing favorably with the combination of pac + ram used in the seminal RAINBOW trial.
Transcriptomic dataset reveals the molecular basis of genotypic variation in hexaploid wheat ( T. aestivum L.) in response to Fe/Zn deficiency - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/32685638/
The datasets depicted in the paper are related to the original article entitled "Identifying transcripts associated with efficient transport and accumulation of Fe and Zn in hexaploid wheat ( T....
Conclusions/Relevance: In real-world routine practice in the US during April 2014 through June 2020, patients with advanced gastric, esophageal, or GEJ cancer who received both RAM and ICI typically received RAM before an ICI, with RAM most commonly administered in 2L therapy. Among the different RAM-containing regimens, RAM + PAC was the...