micro-community-banner
 
  • Saved
Updates from ASH 2025: Treating Older Adults with AML and Managing CAR T–Related Neurotoxicity

This ASH 2025 conference video features expert perspectives on newly published ASH guidelines for the treatment of newly diagnosed older adults with acute myeloid leukemia (AML). Discussion focuses on individualized treatment selection, molecular risk–informed decision-making, assessment of transplant eligibility, and the role of supportive and end-of-life care.

The video also reviews real-world evidence evaluating anti-inflammatory approaches for the management of immune effector cell–associated neurotoxicity syndrome (ICANS) following CAR T-cell therapy, highlighting evolving strategies to address this challenging toxicity in clinical practice.

Share your thoughts

  • Saved
Groundbreaking Advances in Breast Cancer Treatment: Key Trials and New Approaches

Watch as Virginia Kaklamani, MD, and E. Shelley Hwang, MD, discuss the latest breakthroughs in breast cancer care, including promising trials with the potential to lead to FDA approvals and a novel approach to treating DCIS. These insights from the San Antonio Breast Cancer Symposium highlight exciting progress in therapies and strategies shaping the future of breast oncology.

  • Saved
Advancements in Hematology: Long-term Outcomes of Innovative Treatments

In this video, Mikkael A. Sekeres, MD, shares insights from the ASH 2024 meeting on groundbreaking studies in hematology, including promising results for pediatric ALL treatments and the potential of early intervention in myeloma. Dr. Satwanilapur discusses the five-year update on Axocell therapy for indolent lymphoma, demonstrating remarkable long-term survival and remission outcomes. Tune in for the latest breakthroughs in hematologic cancer treatments.

  • Saved
Relapsed Acute Lymphoblastic Leukemia - PubMed

Relapsed Acute Lymphoblastic Leukemia - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/37341952/

Outcomes for children with acute lymphoblastic leukemia (ALL) have improved worldwide to >85%. For those who relapse, outcomes have remained static at ~50% making relapsed acute lymphoblastic leukemia one of...

Outcomes for children with relapsed acute lymphoblastic leukemia (ALL) remain poor. Advances in immunotherapies, cellular therapies, and precision oncology are crucial for improving treatment and outcomes, especially for poor responders.

  • Saved
Therapeutic challenges in peripheral T-cell lymphoma - PubMed

Therapeutic challenges in peripheral T-cell lymphoma - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38178117/

Peripheral T-cell lymphoma (PTCL) is a rare and heterogeneous group of hematological malignancies. Compared to our knowledge of B-cell tumors, our understanding of T-cell leukemia and lymphoma remains less advanced,...

This review explores mechanisms of treatment resistance in peripheral T-cell lymphoma (PTCL), including tumor heterogeneity, microenvironment, and signaling pathways, and discusses drugs and ongoing clinical trials targeting resistance.