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2yr
Caring for an Individual With Chronic Lymphocytic Leukemia (CLL): Understanding Family Caregivers' Perceptions of Social Support, Caregiver Burden, and Unmet Support Needs

Caring for an Individual With Chronic Lymphocytic Leukemia (CLL): Understanding Family Caregivers' Perceptions of Social Support, Caregiver Burden, and Unmet Support Needs

Source : https://link.springer.com/article/10.1007/s13187-023-02392-8

Family caregivers (FCs) of a patient with chronic lymphocytic leukemia (CLL) can encounter unpredictable challenges and care demands. They can experience high levels of burden, a loss of self-care, and...

Statistical analyses showed that family caregivers who perceived they were more supported reported less burden, and female family caregivers reported more burden than males. Support from family, friends, and professionals collectively contributed to family caregiver support.

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2yr
Pirtobrutinib: a Novel Non-Covalent BTK Inhibitor for the Treatment of Adults With Relapsed/Refractory Mantle Cell Lymphoma

Pirtobrutinib: a Novel Non-Covalent BTK Inhibitor for the Treatment of Adults With Relapsed/Refractory Mantle Cell Lymphoma

Source : https://pubmed.ncbi.nlm.nih.gov/38043933/

Pirtobrutinib has demonstrated safety and efficacy in heavily pre-treated adult patients with r/r MCL. Advantages of this drug include its usage in patients whose malignancy is resistant to current BTKi,...

Pirtobrutinib has demonstrated safety and efficacy in heavily pretreated adult patients with R/R MCL.

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2yr
American Society of Hematology Annual Meeting and Exposition

The American Society of Hematology (ASH) is hosting its annual meeting and exposition from Dec. 9 to 12, 2023, in San Diego and online. 

Registration options are available for in-person and virtual attendance. In-person registration grants attendees complimentary access to the virtual meeting platform through Jan. 1, 2024. More information about registration is available on the ASH website.

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2yr

Effect of Delayed Cell Infusion in Patients With Large B-Cell Lymphoma Treated With Chimeric Antigen Receptor T-Cell Therapy

Source : https://haematologica.org/article/view/haematol.2023.284453

Complications occurring after lymphodepleting chemotherapy (LDC) may delay chimeric antigen receptor (CAR) T-cell infusion. The effect of these delays on clinical outcomes is unclear. We performed a retrospective analysis of...

Patients with delayed infusion had lower absolute neutrophil count, lower platelets, lower hemoglobin, and higher C-reactive protein than those with on-time infusion.

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2yr

Pirtobrutinib Versus Venetoclax in Covalent Bruton Tyrosine Kinase Inhibitor-Pretreated Chronic Lymphocytic Leukemia: a Matching-Adjusted Indirect Comparison

Source : https://haematologica.org/article/view/haematol.2023.284150

Venetoclax is a standard treatment for patients with CLL following covalent BTK inhibitor (cBTKi) therapy, despite relatively limited prospective data in this setting. Pirtobrutinib is a highly selective, non-covalent (reversible)...

PFS and OS of pirtobrutinib and venetoclax were comparable in both unweighted and weighted analyses, whereas ORR was significantly higher for pirtobrutinib.