Effectiveness of a Dose-Graded Aerobic Exercise Regimen on Cardiopulmonary Fitness and Physical Performance in Pediatric Survivors of Acute Lymphoblastic Leukemia: a Randomized Clinical Trial
Source : https://pubmed.ncbi.nlm.nih.gov/38267738/
The favorable outcomes of this study bolster the inclusion of D-GAE as a crucial element in the care and rehabilitation of pediatric survivors of ALL. By embracing these findings, healthcare...
The favorable outcomes of this study bolster the inclusion of dose-graded aerobic exercise as a crucial element in the care and rehabilitation of pediatric survivors of ALL.
The Lymphoma Epidemiology of Outcomes Cohort Study: Design, Baseline Characteristics, and Early Outcomes
Source : https://pubmed.ncbi.nlm.nih.gov/38217361/
To address the current and long-term unmet health needs of the growing population of non-Hodgkin lymphoma (NHL) patients, we established the Lymphoma Epidemiology of Outcomes (LEO) cohort study (NCT02736357; https://leocohort.org/)....
Observed OS rates for the Lymphoma Epidemiology of Outcomes cohorts at 1 and 2 years were similar to population-based SEER rates for indolent B- and T-cell lymphomas, but they were 10% to 15% higher than SEER rates for aggressive B-cell subtypes.
Allogeneic CAR-T Cells With of HLA-A/B and TRAC Disruption Exhibit Promising Antitumor Capacity Against B Cell Malignancies
Source : https://pubmed.ncbi.nlm.nih.gov/38231412/
The nU-CAR-T19 cells showed a strong response in R/R B-ALL. nU-CAR-T19 cells have the potential to be a promising new approach for treating R/R B cell malignancies.
Robust expansion of nU-CAR-T19 cells, along with rapid eradication of CD19+ abnormal B cells, was observed in the peripheral blood and bone marrow of another 3 patients with R/R B-ALL.
CanCHD Study of Hematopoietic Cancers in Children With and Without Genetic Syndromes
Source : https://pubmed.ncbi.nlm.nih.gov/38156460/
This is the first large population-based analysis documenting that known genetic syndromes in children with CHD are a significant predictor of HC. The finding could be essential in informing risk-stratified...
Acute myeloid leukemia had a higher cumulative incidence during early childhood than acute lymphoblastic leukemia.
Can Extending Time Between Vital Sign Checks Improve Sleep in Hematopoietic Stem Cell Transplant Patients? Testing Feasibility, Acceptability, and Preliminary Efficacy
Source : https://pubmed.ncbi.nlm.nih.gov/38197636/
Extending time between vitals checks is highly acceptable to patients, caregivers, and nurses, and may offer a feasible approach to improve sleep in pediatric HSCT.
Most patients, caregivers, and nurses reported that patients used the additional 2 hours during the extended time between checking vitals for sleep, with reporters indicating moderate to high acceptability.