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Patient Preferences in the Treatment of Stage III/IV Classic Hodgkin Lymphoma: Results From the CONNECT Cross-Sectional Survey

Patient Preferences in the Treatment of Stage III/IV Classic Hodgkin Lymphoma: Results From the CONNECT Cross-Sectional Survey

Source : https://pubmed.ncbi.nlm.nih.gov/38323849/

We explored patient front-line treatment preferences in newly diagnosed stage III/IV classic Hodgkin lymphoma (cHL). The CONNECT patient survey, administered online from 30 December 2020 to 1 March 2021, examined...

Patients were most concerned at diagnosis about treatment side effects, disruption of life goals and plans, treatment not working and/or cancer becoming worse, the ability to feel normal again, and death.

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Disparity in Treatment Patterns Among Medicare Beneficiaries Diagnosed With Chronic Lymphocytic Leukemia: an Analysis of Patient and Contextual Factors

Disparity in Treatment Patterns Among Medicare Beneficiaries Diagnosed With Chronic Lymphocytic Leukemia: an Analysis of Patient and Contextual Factors

Source : https://pubmed.ncbi.nlm.nih.gov/38323907/

This study characterizes the patterns and timing of CLL treatment and, to our knowledge, is the first to identify social vulnerability factors associated with CLL treatment receipt in the Medicare...

Median time to CLL treatment was 61 days. Older age and residence in a county ranked high in social vulnerability were negatively associated with receiving treatment and time to treatment.

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Follicular Lymphoma Presenting With Symptomatic Bone Involvement: a clinicopathological and Molecular Analysis of 16 Cases

Follicular Lymphoma Presenting With Symptomatic Bone Involvement: a clinicopathological and Molecular Analysis of 16 Cases

Source : https://pubmed.ncbi.nlm.nih.gov/38290600/

Primary bone lymphoma (PBL) is rare and mostly represented by diffuse large B-cell lymphomas (DLBCL). Follicular lymphoma (FL), albeit commonly disseminating to the bone marrow, rarely presents primarily as bone...

At last follow-up, 11 patients achieved complete remission, including all cases with primary bone lymphoma and most patients with limited extraosseous disease.

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Prognostic Impact of Co-Occurring Mutations in FLT3-ITD Pediatric Acute Myeloid Leukemia

Prognostic Impact of Co-Occurring Mutations in FLT3-ITD Pediatric Acute Myeloid Leukemia

Source : https://pubmed.ncbi.nlm.nih.gov/38295280/

We sought to define the co-occurring mutational profile of FLT3-ITD positive (ITDpos) acute myeloid leukemia (AML) in pediatric and young adult patients and to define the prognostic impact of cooperating...

Among the cohort, 79% of patients had co-occurring alterations across 239 different genes that were altered through mutations or fusions.

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Survival Outcomes of Patients With Mantle Cell Lymphoma: a Retrospective, 15-Year, Real-Life Study

Survival Outcomes of Patients With Mantle Cell Lymphoma: a Retrospective, 15-Year, Real-Life Study

Source : https://www.mdpi.com/2038-8330/16/1/6

Mantle cell lymphoma (MCL) prognosis has significantly improved in recent years; however, the possible survival benefit of new treatment options should be evaluated outside of clinical trials. We investigated 73...

The prognosis of MCL has significantly improved in recent years; however, the possible long-term survival benefit of new treatment options has not been clearly established outside of clinical trials.