Prognostic Factors in Philadelphia Chromosome-Positive Acute Myeloid Leukemia Using Fluorescence in Situ Hybridization
Source : https://www.clin-lab-publications.com/article/4773
by Zhaohua Zhang, Chuan Sun, Lingyi Cai, Ying Chen, Xinyi Zhou, Suipeng Chen, Xiao Feng, Xiangchou Yang, Qian Li, Lihua Liu, Haixia Zhou, Baoqing Li Background: Philadelphia chromosome-positive acute myeloid...
Complete remission rate of the patients in this study using conventional chemotherapy was 60% with a median survival of 7.5 months.
Synchronous Plasma Cell Neoplasm and B Lymphoblastic Leukemia/Lymphoma at Initial Presentation: First Report of an Unusual Association With a Good Outcome
Source : https://pubmed.ncbi.nlm.nih.gov/38358598/
A synchronous diagnosis of a plasma cell neoplasm (PCN) and a non-plasma cell hematologic malignancy is very rare. We report what we believe is the first instance of a synchronous...
No prior case of synchronous plasma cell neoplasm and B-ALL at first presentation has been reported to date, and the rarity of all these composite cases suggested that most of them may be coincidental.
ETV6::ACSL6 Translocation-Driven Super-Enhancer Activation Leads to Eosinophilia in Acute Lymphoblastic Leukemia Through IL-3 Overexpression
Source : https://pubmed.ncbi.nlm.nih.gov/38356460/
ETV6::ACSL6 represents a rare genetic aberration in hematopoietic neoplasms and is often associated with severe eosinophilia, which confers an unfavorable prognosis requiring additional anti-inflammatory treatment. However, since the translocation is...
Study findings revealed a cis-regulatory mechanism of super-enhancer translocation in ETV6::ACSL6 ALL, leading to ALL-accompanying clinical syndrome.
Pancreas-Related Persisting Sequelae in ALL Survivors With a History of Asparaginase-Associated Pancreatitis: a Part of the ALL-STAR Study
Source : https://pubmed.ncbi.nlm.nih.gov/38351310/
ALL survivors with AAP are at increased risk of persisting pancreatic dysfunction and require special attention during follow-up.
Levels of pancreatic enzymes were reduced in survivors of acute lymphoblastic leukemia with asparaginase-associated pancreatitis compared with survivors without asparaginase-associated pancreatitis and community controls.
Breast Cancer and Chronic Lymphocytic Leukemia and Renal Cell Carcinoma: a Case Report of a Rare Cancer Combination
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10857808/
The incidence of second malignancies in breast cancer survivors has increased because of early detection and improved cancer treatment modalities. The synchronous occurrence of chronic lymphocytic lymphoma (CLL) and renal...
Considering the continued elevated risk of second cancers in patients with breast cancer and chronic lymphocytic lymphoma in a clinical setting, clinicians should be made aware of ongoing medical surveillance.