Exclusive Breastfeeding Duration and Risk of Childhood Cancers
Source : https://pubmed.ncbi.nlm.nih.gov/38530315/
In this cohort study, longer duration of exclusive breastfeeding was associated with reduced risk of childhood BCP-ALL, corroborating results of previous case-control investigations in this field. To inform future preemptive...
Longer duration of exclusive breastfeeding was associated with reduced risk of childhood BCP-ALL, corroborating results of previous case-control investigations in this field.
Allogeneic Hematopoietic Stem Cell Transplantation After Mogamulizumab in T-Cell Lymphoma Patients: a Retrospective Analysis
Source : https://pubmed.ncbi.nlm.nih.gov/38532079/
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an important therapy for patients with T-cell lymphomas, including cutaneous T-cell lymphoma (CTCL), adult T-cell lymphoma (ATL), and peripheral T-cell lymphoma (PTCL). Mogamulizumab...
GVHD was not associated with the time interval from last mogamulizumab dose to transplantation.
Differential Prognostic Values of the Three AKT Isoforms in Acute Myeloid Leukemia
Source : https://www.nature.com/articles/s41598-024-57578-x
The PI3K-AKT-mTOR pathway lies at the confluence of signaling pathways in which various components are subjected to activating genetic alterations in acute myeloid leukemia (AML), thus contributing to oncogenesis. Three...
A low level of AKT3 expression is strongly correlated to genetic alterations associated with a better outcome, whereas a high level is correlated to alterations associated to a bad outcome.
Lymphomatoid Papulosis With T-Cell Receptor-Gamma Delta Expression: a Clinicopathologic Case-Series of 26 Patients of an Underrecognized Immunophenotypic Variant of Lymphomatoid Papulosis
Source : https://pubmed.ncbi.nlm.nih.gov/38533681/
Lymphomatoid papulosis (LyP) has several histopathologic presentations. LyP featuring gamma-delta (γδ) T-cell receptor expression may masquerade as and may be misdiagnosed as aggressive cutaneous T-cell lymphoma, particularly primary cutaneous γδ...
Pneumocystis Jirovecii Pneumonia in Paediatric Acute Lymphoblastic Leukaemia: a Report From the Multi-International Clinical Trial AIEOP-BFM ALL 2009
Source : https://pubmed.ncbi.nlm.nih.gov/38527954/
Pneumocystis jirovecii can cause life-threatening pneumonia (PjP), and patients with haematological malignancies are at high risk of this infection. Prophylactic measures have significantly decreased morbidity and mortality, but there is...
Pneumocystis jirovecii pneumonia was diagnosed in 6 children (incidence 1/1000) and was associated with insufficient prophylaxis in 5 of them.