Sequential CD7 CAR T-Cell Therapy and Allogeneic HSCT Without GVHD Prophylaxis
Source : https://pubmed.ncbi.nlm.nih.gov/38657244/
Our findings suggest that sequential CD7 CAR T-cell therapy and haploidentical HSCT is safe and effective, with remission and serious but reversible adverse events. This strategy offers a feasible approach...
Sequential CD7 CAR T-cell therapy and haploidentical hematopoietic stem-cell transplantation is safe and effective, with remission and serious but reversible adverse events.
Machine Learning–Based Survival Prediction Models for Progression-Free and Overall Survival in Advanced-Stage Hodgkin Lymphoma
Source : https://pubmed.ncbi.nlm.nih.gov/38608215/
The new prognostic model for aHL on the basis of ML techniques demonstrated a substantial improvement compared with the IPS models, but yielded a limited improvement in predictive performance compared...
The time-varying areas under the curve for the machine learning model and the advanced-stage Hodgkin lymphoma international prognostic index were consistently higher in both cohorts compared with the international prognostic score models within the first 5 years after diagnosis.
Management of Vaccinations in Patients With Non-Hodgkin Lymphoma
Source : https://pubmed.ncbi.nlm.nih.gov/38532527/
Vaccinations are fundamental tools in preventing infectious diseases, especially in immunocompromised patients like those affected by non-Hodgkin lymphomas (NHLs). The COVID-19 pandemic made clinicians increasingly aware of the importance of...
Researchers analyzed the existing data about COVID-19 and other vaccine's efficacy in patients with NHL and propose multidisciplinary team-based recommendations for the management of vaccines in this specific group of patients.
Mitoxantrone Versus Liposomal Daunorubicin in Induction of Pediatric AML With Risk Stratification Based on Flow Cytometry Measurement of Residual Disease
Source : https://pubmed.ncbi.nlm.nih.gov/38603646/
The intensification of induction therapy with risk stratification on the basis of response to induction and hSCT for high-risk patients led to improved outcomes. Mitoxantrone had a superior anti-leukemic effect...
Mitoxantrone had a superior antileukemic effect than liposomal daunorubicin.
Impact of Propofol Exposure on Neurocognitive Outcomes in Children With High-Risk B ALL: a Children's Oncology Group Study
Source : https://pubmed.ncbi.nlm.nih.gov/38603641/
In a multicenter and uniformly treated cohort of children with B-ALL, cumulative exposure to propofol was an independent risk factor for impairment in reaction time/processing speed 1 year after therapy....
Cumulative exposure to propofol was associated with a 0.05 Z score decrease in reaction time/processing speed per each 10-mg/kg exposure of propofol.