Primary lacrimal sac lymphoma: a case-based retrospective study in a Chinese population
Source : https://ies.ijo.cn/gjyken/ch/reader/view_abstract.aspx?file_no=20230406&flag=1
AIM: To determine the clinical characteristics, pathological types, tumor markers, treatments, and outcomes of Chinese patients with primary lacrimal sac lymphoma. METHODS: This case-based retrospective study analyzed 15 Chinese patients...
Conclusion: Early diagnosis and treatment can lead to a good prognosis for most patients with primary lacrimal sac lymphoma. Mass resection combined with DCR can reduce the occurrence of post-surgical epiphora. The pathology type and tumor marker status are associated with prognosis.
Genetic Subdivisions of Follicular Lymphoma Defined by Distinct Coding and non-coding Mutation Patterns
Research Article | Kostiantyn Dreval, Laura K Hilton, Manuela Cruz, Haya Shaalan, Susana Ben-Neriah, Merrill Boyle, Brett J Collinge, Krysta Mila Coyle, Gerben Duns, Pedro Farinha, Bruno Grande, Barbara Meissner,...
Conclusions/Relevance: Using separate validation cohorts, we demonstrate that cFL status, whether assigned with this full classifier or a single-gene approximation, is associated with a reduced rate of HT. This implies distinct biological features of cFL that constrain its evolution and we highlight the potential for this classification to...
A promising prognostic model for predicting survival of patients with HIV-related diffuse large B-cell lymphoma in the cART era - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37081761/
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Conclusions: We developed and validated a simple and feasible prognostic model for patients with HIV-related DLBCL that had more discriminative and predictive accuracy than the IPI score for risk stratification and individualized treatment in the cART era.
Therapeutic Targets in Myelodysplastic Neoplasms: Beyond Hypomethylating Agents - Current Hematologic Malignancy Reports
Source : https://link.springer.com/article/10.1007/s11899-023-00693-9
Purpose of Review To discuss novel targeted therapies under investigation for treatment of myelodysplastic neoplasms (MDS). Recent Findings Over the last few years, results of phase 3 trials assessing novel...
Relevance: In this review, we focus on the current management strategies and novel therapies in development for treatment of high-risk MDS.
Diffuse Large B-Cell Lymphoma Treated With R-CHOP in a Resource-Limited Setting in South Africa: A Real-World Study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37053476/
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Conclusions: Treatment of DLBCL with R-CHOP is feasible and can achieve good outcomes in resource-limited settings with rituximab-based chemotherapy. Poor performance status was the most important adverse prognostic factor in this cohort of HIV-negative patients.