Long-term outcome in patients with mantle cell lymphoma following high-dose therapy and autologous stem cell transplantation - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37094812/
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Conclusion: Sustained long-term clinical and molecular remissions are achievable following ASCT.
Report of consensus panel 7 from the 11th international workshop on Waldenström macroglobulinemia on priorities for novel clinical trials
Source : https://www.sciencedirect.com/science/article/pii/S0037196323000239?via=ihub
Recent advances in the understanding of Waldenström macroglobulinemia (WM) biology have impacted the development of effective novel agents and improve...
Conclusions: CP7 of IWWM-11 considers limited duration of therapy and novel-novel combinations to be the priority for the next generation of clinical trials. Central, validated testing of MYD88, CXCR4 and TP53 is crucial for trial reporting, and MYD88 and CXCR4 should be considered as stratification factors. In the frontline, BR and DRC may...
Patients' experience with chimeric antigen receptor T-cell therapy for DLBCL in China: a qualitative study - Supportive Care in Cancer
Source : https://link.springer.com/article/10.1007/s00520-023-07763-x
Purpose The experiences of patients with diffuse large B-cell lymphoma (DLBCL) treated with chimeric antigen receptor (CAR) T-cell therapy have received little attention. This study aimed to explore the treatment...
Conclusions: The patients experienced short-term and long-term symptoms of physical distress. Patients who have experienced failure in CAR T-cell therapy also experience strong negative emotions, such as dependency and guilt. They also require authentic spiritual and financial information that is authentic. Our study may guide the development...
Breast implant associated EBV-positive Diffuse Large B-cell lymphoma: an underrecognized entity? - Diagnostic Pathology
Source : https://diagnosticpathology.biomedcentral.com/articles/10.1186/s13000-023-01337-5
Breast-implant associated (BIA) lymphoma is an infrequent type of cancer occurring in the fluid and fibrous capsule around a textured breast implant. Recently, both the 2022 WHO 5th edition classification...
Conclusions/Relevance: Such cases, characterized by large CD30-positive cells, can easily be misdiagnosed as BIA-ALCL if the cell of origin is not further established. Therefore, a diagnostic panel including lineage-specific B-and T-cell markers and EBER in situ hybridization is essential to recognize this rare entity, to understand...
Mosunetuzumab monotherapy is active and tolerable in patients with relapsed/refractory diffuse large B-cell lymphoma
Research Article | Nancy L. Bartlett, Sarit Assouline, Pratyush Giri, Stephen J. Schuster, Chan Yoon Y Cheah, Matthew J Matasar, Gareth P. Gregory, Dok-Hyun Yoon, Mazyar Shadman, Keith Fay, Sung-Soo...
Conclusions/Relevance: Mosunetuzumab demonstrated notable efficacy and a manageable safety profile in patients with R/R DLBCL, including those previously treated with CAR-Ts.