Genital Graft Versus Host Disease in Children – an Underdiagnosed and Undertreated Entity
Source : https://pubmed.ncbi.nlm.nih.gov/37926190/
Our case series highlights the significant association between chronic oral and genital GVHD. It is imperative to examine the genital area in all children on follow up for chronic GVHD...
It is imperative to examine the genital area in all children on follow-up for chronic GVHD, because the association between mouth and genital GVHD rate is high and undertreated in children.
Oral Chronic Graft-Versus-Host Disease in Post-Hematopoietic Stem Cell Transplant Patients Following SARS-CoV-2 Vaccination: Case Reports
Source : https://karger.com/cro/article/16/1/1287/869328/Oral-Chronic-Graft-versus-Host-Disease-in-Post
Abstract. Patients receiving allogeneic hematopoietic stem cell transplant may experience graft-versus-host disease (GVHD) in which donor immune cells cause an immune reaction in host tissues. Severe acute respiratory syndrome coronavirus-2...
Patients must be counseled on risks when they receive any vaccine, and HCPs managing patients with GVHD must be aware of the potential to stimulate oral GVHD.
Late-Onset Pneumocystis Jirovecii Pneumonia Post-Allogeneic Stem Cell Transplantation After Time-Dependent Discontinuation of Prophylaxis
Source : https://pubmed.ncbi.nlm.nih.gov/37947314/
There is a need to develop risk-adapted prophylactic strategies in the contemporary era using ATG-based GVHD prophylaxis.
There is a need to develop risk-adapted prophylactic strategies in the contemporary era using ATG-based GVHD prophylaxis.
Understanding the Needs and Lived Experiences of Patients With Graft-Versus-Host Disease: Real-World European Public Social Media Listening Study
Source : https://cancer.jmir.org/2023/1/e42905
Background: Graft-versus-host disease (GVHD) is the major cause of short- and long-term morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Treatment options beyond corticosteroid therapy remain limited, and prolonged...
SM listening is a useful tool to identify medical needs. Treatment of GVHD, including treatment-related side effects, as well as its emotional and physical impact on QoL, are the major topics that GVHD stakeholders mention on SM. We encourage a structured discussion of these topics in interactions between health care providers and patients...
Novel Approaches to Treatment of Acute Myeloid Leukemia Relapse Post Allogeneic Stem Cell Transplantation
Source : https://www.mdpi.com/1422-0067/24/19/15019
The management of patients with acute myeloid leukemia (AML) relapsed post allogeneic hematopoietic stem cell transplantation (HSCT) remains a clinical challenge. Intensive treatment approaches are limited by severe toxicities in...
Despite discordant results, addition of donor lymphocytes infusions generally granted improved outcomes with manageable GvHD incidence. Recent introduction of novel targeted drugs in AML gives the opportunity to add a third element to salvage regimens.