Cardiac Toxicity after Matched Allogeneic Hematopoietic Cell Transplantation in the Post-Transplant Cyclophosphamide Era - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34592759/
2021 Sep 30;bloodadvances.2021004846. doi: 10.1182/bloodadvances.2021004846. Online ahead of print. 1 University of Texas MD Anderson Cancer Center, Houston, Texas, United States. 2 MD Anderson Cancer Center, Houston, Texas, United States....
Mouse Models of Antigen Presentation in Hematopoietic Stem Cell Transplantation - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34594330/
Allogeneic stem cell transplantation (alloSCT) is a curative therapy for hematopoietic malignancies. The therapeutic effect relies on donor T cells and NK cells to recognize and eliminate malignant cells, known...
Vitamin D deficiency after allogeneic hematopoietic cell transplantation promotes T-cell activation and is inversely associated with an EZH2-ID3 signature - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34597852/
Vitamin D promotes a shift from a pro-inflammatory to a more tolerogenic immune state in allogeneic hematopoietic cell transplantation (HCT) recipients. The dominant mechanism responsible for this shift has not...
Delayed administration of ixazomib modifies the immune response and prevents chronic graft-versus-host disease - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34556806/
In this study, we aimed to modify the immune response in the long term after allogeneic bone marrow transplantation (allo-BMT) by using the proteasome inhibitor ixazomib (IXZ) at the late...
Altered effect of killer immunoglobulin-like receptor-ligand mismatch by graft versus host disease prophylaxis in cord blood transplantation - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34561558/
The role of killer immunoglobulin-like receptor-ligand mismatch (KIR-ligand mismatch) between donors and recipients undergoing cord blood transplantation (CBT) is controversial. If each immunosuppressant differently affects natural killer (NK) cell function,...