Mechanisms of Resistance to KRASG12C Inhibitors

Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795113/

KRAS is a gene that is commonly mutated in cancer, especially in pancreatic, lung and colorectal cancers. Despite its importance, scientists have for many years been unable to create a drug that can inhibit function of the KRAS protein. Recently, several ...