TITLE: Multigene PCR using both cfDNA and cfRNA in the supernatant of pleural effusion achieves accurate and rapid detection of mutations and fusions of driver genes in patients with advanced NSCLC
SUMMARY: In advanced NSCLC, pleural effusion makes for good specimens for molecular analysis, and can be quite useful sans tissue samples....
Multigene PCR using both cfDNA and cfRNA in the supernatant of pleural effusion achieves accurate and rapid detection of mutations and fusions of driver genes in patients with advanced NSCLC - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33656807/
1 Department of Pathology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis And Thoracic Tumor Research Institute, Beijing, China. 2 Medical Department, Amoy Diagnostics Co., Ltd., Xiamen, China. 3 Department...
Prognostic impact of KRAS G12C mutation in patients with NSCLC: results from the ETOP Lungscape Project - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33647504/
1 St. James Hospital, Institute of Molecular Medicine, Dublin, Ireland. Electronic address: [email protected]. 2 University Hospital Geneva, Department of Oncology, Geneva, Switzerland. 3 Frontier Science Foundation-Hellas, ETOP Statistics Center and...
Performance evaluation of a fully closed real-time PCR platform for the detection of KRAS p.G12C mutations in liquid biopsy of patients with non-small cell lung cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33649142/
Whenever tissue sample is not available, non-small cell lung cancer (NSCLC) biomarker testing is performed with liquid biopsy. The Kirsten rat sarcoma viral oncogene homolog ( KRAS ) p.G12C mutation...
Novel Emerging Molecular Targets in Non-Small Cell Lung Cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33807876/
In the scenario of systemic treatment for advanced non-small cell lung cancer (NSCLC) patients, one of the most relevant breakthroughs is represented by targeted therapies. Throughout the last years, inhibitors...
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Linnea olson - CancerHacker Lab
Source : https://cancerhackerlab.com/linnea-olson/
Linnea Olson is a well-known advocate for patients and a pioneer in clinical trials for lung cancer. She was diagnosed with non-small cell lung cancer in April of 2005. Linnea...