63-Year-Old Female with Vision Disturbances and Headaches
Evelyn, who is 63, presents to her primary care physician, complaining of headaches, visual disturbances, and fatigue. Her medical history includes hypertension and hyperlipidemia, both under control with medication. She is a former smoker with a 40-pack year history.
Her physical exam is...
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Muhibur Rahman5yrThe patient has a small solitary met in the brain that needs resection. Recently approved Cemiplimab would be one of the choice and of course Clinical trials. RA inhibitor may Show More
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Herman Tong5yrI would trial a clinical trial given her 70% expression of PD-L1
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Transcriptome Based Estrogen Related Genes Biomarkers for Diagnosis and Prognosis in Non-small Cell Lung Cancer
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081391/
Lung cancer is the tumor with the highest morbidity and mortality, and has become a global public health problem. The incidence of lung cancer in men has declined in some...
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Naveed Saleh, MD, MS – Skipta Team5yrKey Points • In the current study, researchers mined the Cancer Genome Atlas (TCGA) for estrogen receptor genes and estrogen signaling pathway genes. They then individually compared the expression of each Show More
Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33947695/
This is the largest molecular study of IMAs to date, where we demonstrate the presence of a major oncogenic driver in nearly all cases. This study is the first to...
Genomic Characterization of Concurrent Alterations in Non-Small Cell Lung Cancer (NSCLC) Harboring Actionable Mutations - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33946519/
An increasing number of driver genomic alterations with potential targeted treatments have been identified in non-small cell lung cancer (NSCLC). Much less is known about the incidence and different distribution...
A Radiogenomics Ensemble to Predict EGFR and KRAS Mutations in NSCLC - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33946756/
Lung cancer causes more deaths globally than any other type of cancer. To determine the best treatment, detecting EGFR and KRAS mutations is of interest. However, non-invasive ways to obtain...