A Sensitive PCR-Based Method for Somatic Mutations Enrichment and Screening - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34737638/
Background: EGFR and KRAS are the most frequently mutated genes in lung cancers, occurring in about 60% of all cases. Mutation genes assay has emerged as a promising blood-based biomarker...
Skin Deep: A Fascinating Case Report of Immunotherapy-Triggered, Treatment-Refractory Autoimmune Lichen Planus and Keratoacanthoma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34703435/
This case discusses a 62-year-old woman with de novo metastatic lung adenocarcinoma (PD-L1 >50% with a KRAS G12C mutation, ALK and EGFR negative) who was on pembrolizumab for 1 year...
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KRAS Oncogene Connect4yrKey Points • Source: Case Reports in Oncology • Conclusion/Relevance: “This case study is on rare auto-immune toxicity as well as a keratoacanthoma from anti-PD-(L) 1 blockade, accompanied by sustained treatment response after cessation Show More
Akt-mediated Ephexin1-Ras interaction promotes oncogenic Ras signaling and colorectal and lung cancer cell proliferation - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34711817/
Ephexin1 was reported to be highly upregulated by oncogenic Ras, but the functional consequences of this remain poorly understood. Here, we show that Ephexin1 is highly expressed in colorectal cancer...
LUNGevity Foundation Launches New Lung Cancer Patient Gateways
WASHINGTON, Oct. 27, 2021 /PRNewswire/ -- LUNGevity Foundation, the nation's leading lung cancer-focused nonprofit organization, has created a new resource: Lung Cancer Patient Gateways. The first to launch is the...
MD Anderson research highlights for October 20, 2021
Source : https://www.eurekalert.org/news-releases/932197
urrent advances include new targeted therapy approaches for chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML), predicting survival following follicular lymphoma treatment, understanding how AML responds to checkpoint blockade...