Application and research progress of BCL2 inhibitors in elderly patients with hematologic malignancies

Source : https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&ved=2ahUKEwiOgfa834PuAhVSh-AKHRRvC1AQFjABegQIBBAC&url=http://www.antpublisher.com/index.php/APT/article/download/336/402&usg=AOvVaw1ilOViOBmuGCSOMqHRo138

Downregulation of microRNA‑25‑3p inhibits the proliferation and promotes the apoptosis of multiple myeloma cells via targeting the PTEN/PI3K/AKT signaling pathway

Source : https://www.spandidos-publications.com/10.3892/ijmm.2020.4841

Numerous studies have confirmed that microRNAs (miRNAs or miRs) have important roles in cancer biogenesis and development including multiple myeloma (MM). MicroRNA‑25‑3p (miR‑25‑3p) has been proven to promote cancer progression,...

Sequential CD19 and BCMA-specific CAR T-cell treatment elicits sustained remission of relapsed and/or refractory myeloma - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33356013/

The low rate of durable response against relapsed and/or refractory multiple myeloma (RRMM) in recent studies indicates that chimeric antigen receptor T-cell (CART) treatment is yet to be optimized. This...