Sequential CD19 and BCMA‐specific CAR T‐cell treatment elicits sustained remission of relapsed and/or refractory myeloma
Source : https://onlinelibrary.wiley.com/doi/pdf/10.1002/cam4.3624
Abstract The low rate of durable response against relapsed and/or refractory multiple myeloma (RRMM) in recent studies indicates that chimeric antigen receptor T‐cell (CART) treatment is yet to be ...
A longitudinal analysis of chromosomal abnormalities in disease progression from MGUS/SMM to newly diagnosed and relapsed multiple myeloma
Source : https://link.springer.com/article/10.1007/s00277-020-04384-w
We analyzed variations in terms of chromosomal abnormalities (CA) by fluorescence in situ hybridization (FISH) analysis on purified bone marrow plasma cells throughout the progression from monoclonal gammopathy of undetermined...
Successful identification of predictive profiles for infection utilising systems‐level immune analysis: a pilot study in patients with relapsed and refractory multiple myeloma
Source : https://onlinelibrary.wiley.com/doi/full/10.1002/cti2.1235
Marcel Doerflinger Corresponding Author Infectious Disease and Immune Defence Division, Walter and Eliza Hall Institute, Parkville, VIC, Australia Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia Correspondence M...
Single Cell RNA-seq Data and Bulk Gene Profiles Reveal a Novel Signature of Disease Progression in Multiple Myeloma
Source : https://www.researchsquare.com/article/rs-135629/v1
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints....
Sequential CD38 monoclonal antibody retreatment leads to deep remission in a patient with relapsed/refractory multiple myeloma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33353443/
We report on a currently 76-year-old female patient with relapsed/refractory (RR) multiple myeloma (MM) treated at our institution. This patient had received six lines of therapy including tandem autologous stem...