Identification of key genes in relapsed multiple myeloma by weighted gene co-expression network analysis
Source : https://www.researchsquare.com/article/rs-153300/v1
Background Multiple myeloma is a hematologic disorder of abnormal plasma cell proliferation. Although there are some agents with different mechanisms in the clinic, the treatment of multiple myeloma is still...
Immunotherapeutic strategies targeting B cell maturation antigen in multiple myeloma
Source : https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-021-00302-x
Multiple myeloma (MM) is the second most common hematologic malignancy, and is characterized by the clonal expansion of malignant plasma cells. Despite the recent improvement in patient outcome due to...
A Phase I Study of a Novel Fully Human BCMA-Targeting CAR (CT103A) in Patients with Relapsed/Refractory Multiple Myeloma | Request PDF
Request PDF | A Phase I Study of a Novel Fully Human BCMA-Targeting CAR (CT103A) in Patients with Relapsed/Refractory Multiple Myeloma | B cell maturation antigen- (BCMA) specific chimeric antigen...
Deciphering spatial genomic heterogeneity at a single cell resolution in multiple myeloma
Source : https://www.researchsquare.com/article/rs-146899/v1
Osteolytic lesions (OL) characterize symptomatic multiple myeloma. The mechanisms of how malignant plasma cells (PC) cause OL in one region while others show no signs of bone destruction despite subtotal...
Alterations of NK Cell Phenotype in the Disease Course of Multiple Myeloma
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