Conclusions/Relevance: Our study shows combining daratumumab with lenalidomide in patients with prior lenalidomide use is a viable and effective treatment option.

Conclusions/Relevance: The goal of this review is to present the infectious complications of CAR T-cell therapy, explain their temporal course and risk factors, and provide recommendations for their prevention, diagnosis, and management.

Conclusions: This study provides relevant contributions to the current knowledge of the CAR-T cell toxicities pathophysiology. Markers of endotheliopathy, innate immunity activation and hemostatic imbalance appear as potential laboratory tools for their prediction, severity and differential diagnosis.

Relevance: In this review, we will focus on the treatment paradigm of relapsed/refractory MM (RRMM) in the era of advanced therapies emphasizing the available novel modalities that have recently been incorporated into routine practice, such as chimeric antigen receptor T-cell therapy, bispecific antibodies, and other promising approaches. We...

Conclusions: Panobinostat-based combination therapies were well-tolerated and yielded modest response rates and CBRs in patients whose disease had been heavily pretreated, over half of whom had disease classified as triple class refractory. Rather than being applied to a broad-based relapsed/refractory multiple myeloma population, the future...