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4yr

Pitfalls in the Diagnosis of Nodular Lymphocyte Predominant Hodgkin Lymphoma: Variant Patterns, Borderlines and Mimics - PubMed

Pitfalls in the Diagnosis of Nodular Lymphocyte Predominant Hodgkin Lymphoma: Variant Patterns, Borderlines and Mimics - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34208705/

Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) represents approximately 5% of Hodgkin lymphoma and typically affects children and young adults. Although the overall prognosis is favorable, variant growth patterns in NLPHL correlate with disease recurrence and progression to T-cell/histiocyte-rich large B-cell lymphoma or frank diffuse large B-cell lymphoma (DLBCL).

  • 4yr
    One of the most challenging mimics of this disease is T cell rich DLBCL and I always recommend to referring physicians a 2nd pathology opinion given the overlapping pathological and clinical features of these conditions

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