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Challenges and Opportunities in the Management of Diffuse Large B-Cell Lymphoma in Older Patients - PubMed

Challenges and Opportunities in the Management of Diffuse Large B-Cell Lymphoma in Older Patients - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33230948/

Most patients with diffuse large B-cell lymphoma (DLBCL) are diagnosed at age 60 years or older. Challenges to effective therapy among older individuals include unfavorable biologic features of DLBCL, geriatric vulnerabilities, suboptimal treatment selection, and toxicities of cytotoxic chemotherapy ...

  • 4yr
    Outcomes in elderly dlbcl are worse than younger patients due to both both disease and patient characteristics. This review highlights present challenges but expresses hope for the future with confined development of novel therapies

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