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Application of high-throughput gene sequencing in lymphoma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33493455/
As a malignant tumor originating from the lymphoid hematopoietic tissues, lymphoma has an increased incidence in recent years and has ranked among the top ten malignant tumors in the world. But until now, due to the multiple pathological subtypes and the unclear molecular mechanism, it's still diffi ...
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Mark Fesler4yrThe only clinically relevant mutations in terms of predictive value lymphomas presently are p53 in mantle cell /CLL and myd88 in waldenstrom. In the case of mantle cell/CLL, we know that those patients probably need alternative strategies to conventional immunochemotherapy For waldenstrom, the presence of the mutation increases the probability of response to btki. This article reviews the potential future expansion of ngs in lymphomas.