Correlation between circulating blood and microenvironment T lymphocytes in diffuse large B-cell lymphomas - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34011621/
Overall, these data suggest that DLBCL with high TME T cells display a pre-existing antitumour immune response. In the rituximab-containing regimen, TME T cells are stimulated further to participate in...
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Mark Fesler4yrThis is a very nice correlative pathological study that makes intuitive endogenous immune system is stronger against dlbcl, the outcome is better
A Systematic Review of the Role of Chimeric Antigen Receptor T (CAR-T) Cell Therapy in the Treatment of Solid Tumors - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34007747/
Chimeric antigen receptor T (CAR-T) cell therapy utilizes patients' own T lymphocytes that are engineered to attack cancer cells. It is Food and Drug Administration (FDA)-approved in various hematological malignancies...
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Mark Fesler4yrThis is a very nice review outlining the challenges and future potential of car T cells for solid cancers.
Key Points
• This prospective observational study involved the humoral immunogenicity of the seasonal inactivated influenza vaccine (IIV) in the context of CD19-, CD20-, and BCMA-targeted CAR-T-cell therapy. The participants were vaccinated either before or after CAR-T-cell therapy, and responses were compared with those of controls.
• The...
Humoral immunogenicity of the seasonal influenza vaccine before and after CAR-T-cell therapy - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34013294/
This article is a preprint Preprints have not been peer reviewed. Learn more about preprints in the NIH Preprint Pilot. Recipients of chimeric antigen receptor-modified T (CAR-T) cell therapies for...
Cardiovascular disease risks in younger versus older adult B-cell non-Hodgkin's lymphoma survivors - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33979029/
doi: 10.1002/cam4.3934. Online ahead of print. 1 Division of Public Health, Department of Family & Preventive Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA. 2 Huntsman...
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Naveed Saleh, MD, MS – Skipta Team4yrKey Points • In the current epidemiology study, researchers mined the Utah Cancer Registry to assess cardiovascular disease (CVD) risk among younger versus older B-cell non-Hodgkin's lymphoma (B-NHL) survivors. They also Show More
Collision Tumor Comprising Primary Malignant Lymphoma and Adenocarcinoma in the Ascending Colon - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33976615/
We describe the case of a 78-year-old man with collision tumor from the primary malignant lymphoma and adenocarcinoma in the ascending colon. He suffered anemia from sigmoid colon cancer, and...