Head-to-head comparison of in-house produced CD19 CAR-T cell in ALL and NHL patients - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/32152221/

doi: 10.1136/jitc-2019-000148. 1 Ella Lemelbaum Institute for Immuno Oncology, Sheba Medical Center, Tel Hashomer, Israel. 2 Division of Pediatric Hematology and Oncology, The Edmond and Lily Safra Children's Hospital, Sheba...

Association of the Geriatric 8 with treatment intensity and prognosis in older patients with diffuse large B-cell lymphoma - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34041751/

Because of the heterogeneity among older patients with diffuse large B-cell lymphoma (DLBCL), the establishment of an easy-to-use geriatric assessment tool is an unmet need. We verified the impact of...

Dynamic changes in peripheral blood lymphocyte subset counts and functions in patients with diffuse large B cell lymphoma during chemotherapy - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34044841/

The absolute counts and functions of CD4 + , CD8 + T cells, which were significantly lower in patients with DLBCL, gradually recovered after effective treatment. Therefore, combined detection of...

Diagnostic accuracy of pelvic magnetic resonance imaging for the assessment of bone marrow involvement in diffuse large B-cell lymphoma - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34043683/

Pelvic MRI is effective for detecting BMinv in DLBCL patients, providing a more accurate indication of PFS than BMB/BMS and PET/CT do. It may ultimately be used to improve the...

Mechanisms of resistance to CAR T cell therapy - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/30837712/

The successes with chimeric antigen receptor (CAR) T cell therapy in early clinical trials involving patients with pre-B cell acute lymphoblastic leukaemia (ALL) or B cell lymphomas have revolutionized anticancer...