Comprehensive Characterization of Cachexia-Inducing Factors in Diffuse Large B-Cell Lymphoma Reveals a Molecular Subtype and a Prognosis-Related Signature - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34079795/
This study demonstrated that CIFs further contribute to the observed heterogeneity of DLBCL, and molecular classification and a risk signature based on CIFs are both promising tools for prognostic stratification,...
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Mark Fesler4yrEye opening article elaborating cachexia factors and importance in dlbcl prognosis
Value of total lesion glycolysis and cell-of-origin subtypes for prognostic stratification of diffuse large B-cell lymphoma patients - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34079720/
The TLG, cell-of-origin subtypes, and NCCN-IPI are independent prognostic survival factors in DLBCL patients. Moreover, the revised risk model composed of the number of risk factors (high TLG, non-GCB, and...
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Mark Fesler4yrThis is an interesting retrospective study demonstrating the prognostic value of pet/ct total lesions glycolysis plus disease subtype plus nccn ipi with development of a new score for outcome prediction.
Successful Management of a Patient with Refractory Primary Central Nervous System Lymphoma by Zanubrutinib - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34079282/
Primary central nervous system lymphoma (PCNSL) is a rare subtype of extranodal non-Hodgkin lymphoma, and the most frequent histological type is diffuse large B-cell lymphoma (DLBCL). Bruton's tyrosine kinase inhibitor...
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Naveed Saleh, MD, MS – Skipta Team4yrKey Points • In the current case report, investigators documented the successful treatment of a 53-year-old patient with refractory primary central nervous system lymphoma (PCNSL) using the small molecule inhibitor zanubrutinib. • Show More
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Mark Fesler4yrClinically useful article demonstrating that a next gen btki can penetrate cns and treat pcns....
CD24 Contributes to Treatment Effect in ABC-DLBCL Patients with R-CHOP Resistance - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34079334/
1 Department of Stomatology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, People's Republic of China. 2 Department of Clinical Laboratory, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,...
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Mark Fesler4yrCd24 as measured by rna expression seems to correlate positively with outcome in abc subset of DLBCL ...further work should be confirmatory and perhaps identify a readily available test
Baseline 18F-FDG PET textural features as predictors of response to chemotherapy in diffuse large B-cell lymphoma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34075009/
doi: 10.1097/MNM.0000000000001447. Online ahead of print. 1 Department of Nuclear Medicine, University of Health Sciences, Ankara City Hospital Department of Medical Informatics, Middle East Technical University, Informatics Institute Department of...
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Mark Fesler4yrFascinating article showing that suvmax and textural heterogeneity of the tumor are responsible for unsatisfactory frontline treatment results. The study is rather small but if confirmed in a larger Show More