Characterization of GECPAR, a noncoding RNA that regulates the transcriptional program of diffuse large B cell lymphoma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34162177/
Enhancers are regulatory regions of DNA, which play a key role in cell-type specific differentiation and development. Most active enhancers are transcribed into enhancer RNAs (eRNAs) that can regulate transcription...
Prophylaxis with intrathecal or high-dose methotrexate in diffuse large B-cell lymphoma and high risk of CNS relapse - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34135307/
Although methotrexate (MTX) is the most widely used therapy for central nervous system (CNS) prophylaxis in patients with diffuse large B-cell lymphoma (DLBCL), the optimal regimen remains unclear. We examined...
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Naveed Saleh, MD, MS – Skipta Team4yrKey Points • In the current study, researchers compared the efficacy of different prophylactic regimens in 585 newly diagnosed DLBCL patients at high-risk for CNS relapse. These participants were treated with Show More
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Naveed Saleh, MD, MS – Skipta Team4yrKey Points • Methotrexate (MTX) is the most popular means of CNS prophylaxis in patients with diffuse large B-cell lymphoma (DLBCL), however the best regimen for its administration remain to be Show More
Identification of a prognostic metabolic gene signature in diffuse large B-cell lymphoma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34128320/
Diffuse large B-cell lymphoma (DLBCL) is a clinically diverse disease. Given the numerous genetic mutations and variations associated with it, a prognostic gene signature that can be related to the...
Aberrant expression of multiple T cell markers on diffuse large B cell lymphoma: a case report - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34129157/
The case presented as a diagnostic dilemma for the pathologist. The predicament lies in classifying it as a B cell lymphoma with an aberrant expression of T cell markers versus...
Extranucleolar CYCLON Staining Pattern Is Strongly Associated to Relapse/Refractory Disease in R-CHOP-treated DLBCL - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34131636/
doi: 10.1097/HS9.0000000000000598. 1 Department of Cytology and Pathology, Grenoble-Alpes University Hospital, Grenoble, France. 2 Institute for Advanced Biosciences, INSERM U1209/CNRS UMR 5309/Grenoble Alpes University, Grenoble, France. 3 Department of Clinical...