Salvage radiotherapy for primary refractory and relapsed diffuse large B-Cell lymphoma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34378402/
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma, accounting for 30-40% of all non-Hodgkin lymphoma cases and presenting later in life, most often in the...
Whole genome sequencing demonstrates substantial pathophysiological differences of MYC rearrangements in patients with plasma cell myeloma and B-cell lymphoma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34380369/
MYC rearrangements ( MYC r) occur in several B-cell neoplasms and impact disease progression and overall survival. We used whole genome sequencing (WGS) and whole transcriptome sequencing (WTS) to analyze...
Identification of Hub Genes and Pathways Associated with CAR-T Cell-Mediated Neurotoxicity in DLBCL - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34383407/
In DLBCL microenvironment before CAR-T cell infusion, we identified T cell activation and glycolysis pathways significantly associated with CAR-T cell-mediated severe neurotoxicity. GZMB might be used as a predictive and...
High-dose methotrexate is effective for prevention of isolated CNS relapse in diffuse large B cell lymphoma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34385415/
The role of central nervous system (CNS) prophylaxis with high-dose methotrexate (HDMTX) in DLBCL is controversial. In this retrospective study, we evaluated the efficacy of prophylactic HDMTX on isolated CNS...
Epstein-Barr Virus Positive B-Cell Lymphoproliferative Disorder of the Gastrointestinal Tract - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34359715/
1 Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya 466-8560, Japan. 2 Department of Surgical Pathology, Aichi Medical University Hospital, Nagakute 480-1195, Japan. 3 Department of...
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Naveed Saleh, MD, MS – Skipta Team4yrKey Points • Conclusion/Relevance: “Epstein-Barr virus positive B-cell lymphoproliferative disorder (EBV+ B-LPD) encompasses a broad clinicopathological spectrum and distinct clinical behavior that relatively favors the gastrointestinal (GI) tract. In this review, Show More