Single-cell transcriptome analysis of diffuse large B cells in cerebrospinal fluid of central nervous system lymphoma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34471864/
Diffuse large B cells in the cerebrospinal fluid (CSF-DLBCs) have offered great promise for the diagnostics and therapeutics of central nervous system lymphoma (CNSL) leptomeningeal involvement. To explore the phenotypic...
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DLBCL Connect4yrKey Points • Conclusion/Relevance: “Taken together, our findings firstly investigated systematic and comprehensive transcriptome characteristics of more than one thousand CSF-DLBCs at the single-cell level. We discovered that most CSF-DLBCs displayed immunoglobulin Show More
Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34478526/
Primary bone diffuse large B-cell lymphoma (PB-DLBCL) is a rare extranodal lymphoma subtype. This retrospective study elucidates the currently unknown genetic background of a large clinically well-annotated cohort of DLBCL...
PET-CT in patients with DLBCL treated with CAR-T cell therapy: a practical approach of reporting pre- and post-treatment studies - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34480603/
doi: 10.1007/s00259-021-05551-5. Online ahead of print. 1 Department of Nuclear Medicine, Tel-Aviv Sourasky Medical Center, 6 Weizmann St, 6423906, Tel Aviv, Israel. 2 Institute of Hematology, Tel-Aviv Sourasky Medical Center,...
Factors affecting survival in elderly patients with diffuse large B-Cell lymphoma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34481125/
Advancing age was a poor prognostic factor for survival of DLBCL. Relapsing within the first year, or failure to achieve complete remission were associated with poorer survival of the elderly...
A prospective study on early PET/CT scans during the first cycle of salvage chemotherapy for relapsed or refractory diffuse large B-cell lymphoma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34435552/
Many patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) will not respond to platinum-containing salvage chemotherapy. Predicting treatment failure earlier could help clinicians minimize chemotherapy toxicities for non-responders...