Prostate Cancer Connect
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Utility of radiomic zones for risk classification and clinical outcome predictions using supervised machine learning during simultaneous 11 C-choline PET/MRI acquisition in prostate cancer patients - PubMed

Utility of radiomic zones for risk classification and clinical outcome predictions using supervised machine learning during simultaneous 11 C-choline PET/MRI acquisition in prostate cancer patients - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34214211/

We proposed three radiomic zones with different standard uptake value characteristics and created four risk groups of prostate cancer patients for testing this idea. We showed these radiomic zones have...

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The BARCODE1 Pilot: a feasibility study of using germline SNPs to target prostate cancer screening - PubMed

The BARCODE1 Pilot: a feasibility study of using germline SNPs to target prostate cancer screening - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34214236/

The BARCODE1 pilot has shown this community study in the UK to be feasible, with an overall uptake of 26%. The main BARCODE1 study is now open and will recruit...

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Contemporary Analysis of Electronic Frailty Measurement in Older Adults with Multiple Myeloma Treated in the National US Veterans Affairs Healthcare System - PubMed

Contemporary Analysis of Electronic Frailty Measurement in Older Adults with Multiple Myeloma Treated in the National US Veterans Affairs Healthcare System - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34207459/

Electronic frailty indices based on data from administrative claims and electronic health records can be used to estimate frailty in large populations of older adults with cancer where direct frailty...

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MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells - PubMed

MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34163028/

The polybromo-associated PBAF (SWI/SNF) chromatin remodeling complex, which includes PBRM1, ARID2, and BRD7, regulates cell differentiation and genomic integrity. MUC1-C is an oncogenic protein that drives lineage plasticity in prostate...