Utility of radiomic zones for risk classification and clinical outcome predictions using supervised machine learning during simultaneous 11 C-choline PET/MRI acquisition in prostate cancer patients - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34214211/
We proposed three radiomic zones with different standard uptake value characteristics and created four risk groups of prostate cancer patients for testing this idea. We showed these radiomic zones have...
The BARCODE1 Pilot: a feasibility study of using germline SNPs to target prostate cancer screening - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34214236/
The BARCODE1 pilot has shown this community study in the UK to be feasible, with an overall uptake of 26%. The main BARCODE1 study is now open and will recruit...
Contemporary Analysis of Electronic Frailty Measurement in Older Adults with Multiple Myeloma Treated in the National US Veterans Affairs Healthcare System - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34207459/
Electronic frailty indices based on data from administrative claims and electronic health records can be used to estimate frailty in large populations of older adults with cancer where direct frailty...
MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34163028/
The polybromo-associated PBAF (SWI/SNF) chromatin remodeling complex, which includes PBRM1, ARID2, and BRD7, regulates cell differentiation and genomic integrity. MUC1-C is an oncogenic protein that drives lineage plasticity in prostate...