Single-Center Experience of Focal Thermo-Ablative Therapy After Pelvic Radiotherapy for In-Field Prostate Cancer Oligo-Recurrence - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34381730/
In PCa patients showing in-field oligo-recurrence after pelvic radiotherapy, focal ablative treatment is a feasible option, possibly delaying a systemic treatment initiation or modification. These invasive strategies should preferably be...
Optimization of polyethylene glycol-based hydrogel rectal spacer for focal laser ablation of prostate peripheral zone tumor - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34364254/
doi: 10.1016/j.ejmp.2021.07.034. Online ahead of print. 1 Department of Mechanical Engineering, K. N. Toosi University of Technology, Tehran, Iran. 2 Department of Mechanical Engineering, K. N. Toosi University of Technology,...
Designed, synthesized and biological evaluation of proteolysis targeting chimeras (PROTACs) as AR degraders for prostate cancer treatment - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34364224/
As a continuation of our research on developing potent and potentially safe androgen receptor (AR) degrader, a series of novel proteolysis targeting chimeras (PROTACs) containing the phthalimide degrons with different...
Regional differences in patient age and prostate cancer characteristics and rates of treatment modalities in favorable and unfavorable intermediate risk prostate cancer across United States SEER registries - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34364187/
doi: 10.1016/j.canep.2021.101994. Online ahead of print. 1 Department of Urology, University Hospital Frankfurt, Frankfurt am Main, Germany; Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health...
Molecular analysis of cell survival and death pathways in the proteasome inhibitor bortezomib-resistant PC3 prostate cancer cell line - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34363546/
The ubiquitin-proteasome pathway is an important protein quality control system involved in intracellular homeostasis. To achieve intracellular homeostasis, proteins that are misfolded as a result of translational errors or genetic...