Functional characterization of HIC, a P2Y1 agonist, as a p53 stabilizer for prostate cancer cell death induction - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34505540/

doi: 10.4155/fmc-2021-0159. Online ahead of print. 1 Molecular Signaling Lab, Faculty of Medicine & Health Technology, Tampere University, Finland. 2 BioMeditech & Tays Cancer Center, Tampere University Hospital, PO Box...

Clinical outcomes of salvage treatment in lymph node-positive prostate cancer patients after radical prostatectomy - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34506516/

In patients with LNP prostate cancer, salvage ADT plus RT improved 2nd BCF and PFS compared to ADT alone. In particular, when the patients had more than two positive lymph...

Circulating Cell-Free DNA-Based Detection of Tumor Suppressor Gene Copy Number Loss and Its Clinical Implication in Metastatic Prostate Cancer - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34504797/

Current liquid biopsy assays lack sufficient sensitivity to detect copy number loss, which limits the interrogation of critical tumor suppressor gene deletions during cancer progression and treatment. Here we describe...

Positivity Rate of [ 18 F]Fluciclovine PET/CT in Patients with Suspected Prostate Cancer Recurrence at PSA Levels Below 1 ng/mL - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34480289/

Despite low PSA values, more than half of patients had positive [ 18 F]fluciclovine PET/CT findings. Patients with low PSA levels may demonstrate suspicious findings outside of the pelvis, including...

The evolution of image guidance in robotic-assisted laparoscopic prostatectomy (RALP): a glimpse into the future - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34480674/

doi: 10.1007/s11701-021-01305-5. Online ahead of print. 1 Royal Prince Alfred Institute of Academic Surgery, Camperdown, Sydney, NSW, 2050, Australia. [email protected]. 2 Concord Repatriation General Hospital, Sydney, NSW, Australia. [email protected]. 3...