Prostate Cancer Connect
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Machine log file-based dose verification using novel iterative CBCT reconstruction algorithm in commercial software during volumetric modulated arc therapy for prostate cancer patients - PubMed

Machine log file-based dose verification using novel iterative CBCT reconstruction algorithm in commercial software during volumetric modulated arc therapy for prostate cancer patients - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34837857/

doi: 10.1016/j.ejmp.2021.11.004. Online ahead of print. 1 Department of Radiation Oncology, Osaka International Cancer Institute, Osaka, Japan; Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Suita,...



Conclusion/Relevance: A similar machine log file-based dose verification accuracy is obtained for FDK-CBCT and iCBCT during VMAT for prostate cancer patients.

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A prostate cancer tissue specific spectral library for targeted proteomic analysis - PubMed

A prostate cancer tissue specific spectral library for targeted proteomic analysis - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34799972/

doi: 10.1002/pmic.202100147. Online ahead of print. 1 Zhejiang University, Hangzhou, China. 2 Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, 310024, China. 3...



Conclusion: Here we provide a comprehensive tissue-specific spectral library for targeted proteomic analysis of prostate tissue samples. Benign and malignant FFPE prostate tissue samples were processed into peptide samples by pressure cycling technology (PCT)-assisted sample preparation, and fractionated with high-pH reversed phase...

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Targeted fluorescent imaging of a novel FITC-labeled PSMA ligand in prostate cancer - PubMed

Targeted fluorescent imaging of a novel FITC-labeled PSMA ligand in prostate cancer - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34800176/

doi: 10.1007/s00726-021-03102-8. Online ahead of print. 1 Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, 100853, China. 2 Department of Nuclear Medicine, Chinese PLA General Hospital, Beijing, 100853, China....


Conclusion:A novel FITC-labeled PSMA ligand (PSMA-FITC) was synthesized by Fmoc solid-phase synthesis. PSMA-FITC has high sensitivity and specificity for PSMA( ) prostate cancer. The rapid targeting and high tumor-background contrast of PSMA-FITC proved that PSMA ligand-mediated prostate cancer-targeted fluorescence imaging has high potential...

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    • Source: Amino Acids • Conclusion/Relevance: “PSMA-FITC is a promising probe and has important reference value for the development of PSMA fluorescent probes. In the future, it can be applied to obtain accurate Show More
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Novel combination therapy of prostate cancer cells with arsenic trioxide and flutamide: An in-vitro study - PubMed

Novel combination therapy of prostate cancer cells with arsenic trioxide and flutamide: An in-vitro study - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34800879/

doi: 10.1016/j.tice.2021.101684. Online ahead of print. 1 Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran. 2 Women's College Research Institute, Women's College Hospital, University of Toronto, Canada; Institute...


Conclusion: The combination therapy with ATO and flutamide has augmented the anti-tumor effect on LNCaP and PC3 cells, which probably originates from their potential to induce apoptosis and inhibit the proliferation of PCa cells simultaneously.

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68 Ga-PSMA PET/CT for response assessment and outcome prediction in metastatic prostate cancer patients treated with taxane-based chemotherapy - PubMed

68 Ga-PSMA PET/CT for response assessment and outcome prediction in metastatic prostate cancer patients treated with taxane-based chemotherapy - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34772793/

Aim: We aimed to evaluate the role of Positron Emission Tomography (PET) targeting the Prostate-Specific Membrane Antigen (PSMA) for response assessment in metastatic prostate cancer (mPCa) patients treated with taxane-based...


This retrospective analysis suggests that 68Ga-PSMA-11 PET/CT is a promising imaging modality for assessing response to taxane-based chemotherapy in mPCa. PSMA-expression changes might be used as a predictive biomarker for OS which might help tailor individual therapy and select eligible patients for clinical trials.