Prostate Cancer Connect
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Case Report: Role of an Iodinated Rectal Hydrogel Spacer, SpaceOAR Vue™, in the Context of Low-Dose-Rate Prostate Brachytherapy, for Enhanced Post-Operative Contouring to Aid in Accurate Implant Evaluation and Dosimetry - PubMed

Case Report: Role of an Iodinated Rectal Hydrogel Spacer, SpaceOAR Vue™, in the Context of Low-Dose-Rate Prostate Brachytherapy, for Enhanced Post-Operative Contouring to Aid in Accurate Implant Evaluation and Dosimetry - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35004333/

We present a case series of 13 consecutive patients with prostate cancer treated with low-dose-rate (LDR) brachytherapy, utilizing SpaceOAR Vue™, the recent iodinated iteration of the SpaceOAR™ hydrogel rectal spacer....


Relevance: Not previously described in the literature in the context of LDR brachytherapy, we demonstrate the added clinical benefit of placing a well-visualized rectal spacer.

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Intensity-modulated radiation therapy for prostate cancer after rectal surgery: a single hospital long-term safety analysis - PubMed

Intensity-modulated radiation therapy for prostate cancer after rectal surgery: a single hospital long-term safety analysis - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35122170/

doi: 10.1007/s10147-022-02124-w. Online ahead of print. 1 Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. 2 Department of...


Conclusions: This retrospective analysis suggested that IMRT for patients with prostate cancer after rectal surgery may be safe and effective with rectal dose constraint of Dmax

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Racial disparities in prostate cancer: A complex interplay between socioeconomic inequities and genomics

Racial disparities in prostate cancer: A complex interplay between socioeconomic inequities and genomics

Source : https://www.sciencedirect.com/science/article/abs/pii/S0304383522000441?via=ihub

Black men are 2.14 times more likely to die from prostate cancer compared to White men. * Equalizing access-to-quality-care is unlikely to fully eliminate racial health disparities. * Significant differences...


Conclusion: Immediate actions are needed to increase the establishment of adequate infrastructure and multi-center, interdisciplinary research to bridge the gap between social and biological determinants of prostate cancer health disparities.

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Evaluation of hyaluronic acid gel dissolution with hyaluronidase in an in-vitro prostate cancer model - PubMed

Evaluation of hyaluronic acid gel dissolution with hyaluronidase in an in-vitro prostate cancer model - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35036588/

A dose response was observed by HAS injection: highest volumes of HAS dissolute most swiftly. Using a ratio of HA:HAS of 1:2 results in a decrease to half of initial...


Conclusions: A dose response was observed by HAS injection: highest volumes of HAS dissolute most swiftly. Using a ratio of HA:HAS of 1:2 results in a decrease to half of initial volume within 24 h. This is of special interest when used in clinical practice following erroneous positioning, and dissolution is urgently needed.

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Survival Outcomes in Men with Unfavorable Intermediate-Risk and High-Risk Prostate Cancer Treated with Prostate-only versus Whole Pelvic Radiation Therapy

Survival Outcomes in Men with Unfavorable Intermediate-Risk and High-Risk Prostate Cancer Treated with Prostate-only versus Whole Pelvic Radiation Therapy

Source : https://www.auajournals.org/doi/10.1097/JU.0000000000002455

DISCLOSURES: The American Urological Association (AUA) is committed to maintaining transparency in its relationships. The AUA requires that individuals make full disclosures for themselves, their family and/or business partner of...


Conclusions: Men with higher LN risk scores and Gleason grade benefited from WPRT. These results complement the recent POP-RT randomized trial in mostly PET/CT-staged patients, demonstrating that a more heterogenous population of men staged without functional imaging benefit from WPRT.