Bone Uptake in Prostate Cancer Patients: Diagnostic Performances of PSMA-RADS v1.0, Clinical, Biological, and 68Ga-PSMA-11 PET Features to Predict Metastasis After Biochemical Recurrence - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35543633/
doi: 10.1097/RLU.0000000000004259. Online ahead of print. 1 From the Departments of Nuclear Medicine. 2 ICO René Gauducheau, F-44800 Saint-Herblain, Nantes Université, Univ Angers, INSERM, CNRS, CRCI2NA, F-44000 Nantes. 3 Department...
Conclusions: Most bone uptakes at PSMA PET/CT were benign lesions. PSMA-RADS, patients and tumor characteristics, and SUVmax could help identify PCa bone metastases.
Inter-Reader Variability Using PI-RADS v2 Versus PI-RADS v2.1: Most New Disagreement Stems from Scores 1 and 2 - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35545106/
doi: 10.1055/a-1752-1038. Online ahead of print. 1 Department of Radiology, Charite University Hospital Berlin, Germany. 2 Department of Biometry and Clinical Epidemiology, Charite University Hospital Berlin, Germany. 3 Biostatistics and...
Conclusion: PI-RADS v2.1 improves inter-reader agreement in the PZ. New differences in inter-reader agreement were mainly the result of the assignment of PI-RADS v2.1 scores 1 and 2 to lesions in the TZ. Combining scores 1 and 2 improved inter-reader agreement both in the TZ and in the PZ, indicating that refined definitions may be warranted...
Quality of life after definitive linear accelerator-based stereotactic radiotherapy for prostate cancer: a longitudinal study - Radiation Oncology
Source : https://ro-journal.biomedcentral.com/articles/10.1186/s13014-022-02061-y
Background Prostate cancer is the second most common malignancy worldwide, and the majority of patients are diagnosed with localized disease. We examined patients' quality of life after stereotactic body radiation...
Conclusions: This study showed longitudinal changes in quality of life by FACT-P after SBRT for prostate cancer. Overall, prostate SBRT was well tolerated.
PARP Inhibition, a New Therapeutic Avenue in Patients with Prostate Cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35511402/
Up to 25% of patients with metastatic prostate cancer present with germline or somatic DNA damage repair alterations, some of which are associated with aggressive disease and poor outcomes. New...
Conclusion: Herein, we review the rationale for PARP inhibition in patients with prostate cancer, discuss the impact of PARP inhibitors on outcomes, and explore underlying challenges for future developments.
Impact of hydrogel peri-rectal spacer insertion on seminal vesicles intrafraction motion during 1.5 T-MRI-guided adaptive stereotactic body radiotherapy for localized prostate cancer
Source : https://www.birpublications.org/doi/10.1259/bjr.20210521
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Conclusions: A favorable impact of the hydrogel-spacer on seminal vesicles motion was observed only in cranio-caudal translational shifts, although being not clinically significant. Further studies are required to fully investigate the potential contribution of this device on vesicles motion.