A deep learning network for Gleason grading of prostate biopsies using EfficientNet
Source : https://www.degruyter.com/document/doi/10.1515/bmt-2022-0201/html
Objectives The most crucial part in the diagnosis of cancer is severity grading. Gleason's score is a widely used grading system for prostate cancer. Manual examination of the microscopic images...
Conclusions: "The proposed network was able to outperform the existing methods and it achieved an Kappa score of 0.5775."
IRONMAN: A Novel International Registry of Men With Advanced Prostate Cancer
Source : https://ascopubs.org/doi/10.1200/GO.22.00154
PURPOSE To describe a newly established international registry recruiting diverse patients with advanced prostate cancer across academic and community practices to address unmet needs in this population. PATIENTS AND METHODS...
Conclusions: To our knowledge, this is the first international cohort of people newly diagnosed with advanced prostate cancer designed to describe variations in patient management, experiences, and outcomes. IRONMAN aims to identify optimal treatment sequences to improve survival, understand patient-reported outcomes, and explore novel...
MRI-based analysis of different clinically significant prostate cancer detection rate of prostate imaging reporting and data system score 4 in the peripheral zone - Abdominal Radiology
Source : https://link.springer.com/article/10.1007/s00261-022-03712-0
Purpose To compare the clinically significant prostate cancer (csPCa) detection rate between diffusion-weighted imaging (DWI) 4 and DWI 3 with positive dynamic contrast-enhanced (DCE) (hereinafter called 'DWI 3/DCE+') lesions in...
Conclusions: DWI 4 tends to have worse results than DWI 3/DCE . TB has great diagnostic performances in DWI 3/DCE patients, especially for those prostate-specific antigen ranging from 4 to 10 ng/mL.
Hyaluronic acid rectal spacer in EBRT: Usability, safety and symmetry related to user experience - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36202722/
Injection of HA was able to achieve highly symmetrical recto-prostatic separation, with new users able to produce excellent separation, particularly at the apex, achieving similar dosimetry outcomes as competent and...
Conclusions: Injection of HA was able to achieve highly symmetrical recto-prostatic separation, with new users able to produce excellent separation, particularly at the apex, achieving similar dosimetry outcomes as competent and experienced users. HA is safe, easy to use, and significantly reduced mean rV70Gy and rV53Gy compared to non-spacer...
AI-based prostate analysis system trained without human supervision to predict patient outcome from tissue samples
Source : https://www.sciencedirect.com/science/article/pii/S2153353922007313?via=ihub
In order to plan the best treatment for prostate cancer patients, the aggressiveness of the tumor is graded based on visual assessment of tissue biopsies according to the Gleason scale....
Relevance: We have trained an AI to predict patient outcome directly based on image analysis of a large biobank of tissue samples with known outcome without input of any human knowledge about cancer grading. The model has shown similar and in some cases better ability to predict patient outcome on an independent test-set than expert...