Management of Patients with Advanced Prostate Cancer. Part I: Intermediate-/High-risk and Locally Advanced Disease, Biochemical Relapse, and Side Effects of Hormonal Treatment: Report of the Advanced Prostate Cancer Consensus Conference 2022
Source : https://pubmed.ncbi.nlm.nih.gov/36494221/
The Advanced Prostate Cancer Consensus Conference (APCCC) provides a forum to discuss and debate current diagnostic and treatment options for patients with advanced prostate cancer. The conference aims to share...
The APCCC 2022 findings underscore the need for personalized prostate cancer care, integrating current evidence, patient factors, and research gaps to guide clinical decisions and prioritize future investigations.
Biomarkers of Aggressive Prostate Cancer at Diagnosis
Source : https://pubmed.ncbi.nlm.nih.gov/36768533/
In the United States, prostate cancer (CaP) remains the second leading cause of cancer deaths in men. CaP is predominantly indolent at diagnosis, with a small fraction (25-30%) representing an...
We discuss some of the adjunctive biomarker tests along with newer imaging modalities that are currently available to help clinicians decide which patients are at risk of having high-grade CaP on prostate biopsy with the emphasis on clinical utility of the tests across African American (AA) and Caucasian (CA) men.
Applications of Artificial Intelligence in Prostate Cancer Care: A Path to Enhanced Efficiency and Outcomes
Source : https://pubmed.ncbi.nlm.nih.gov/38935882/
The landscape of prostate cancer care has rapidly evolved. We have transitioned from the use of conventional imaging, radical surgeries, and single-agent androgen deprivation therapy to an era of advanced...
This review highlights AI's transformative potential in prostate cancer care, emphasizing challenges such as data privacy, interpretability, and integration into clinical workflows. Human-AI collaboration is envisioned for enhancing decision-making and patient outcomes while preserving clinical judgment and ethical standards.
Photoacoustic imaging in prostate cancer: A new paradigm for diagnosis and management
Source : https://pubmed.ncbi.nlm.nih.gov/38821240/
The global health issue of prostate cancer (PCa) requires better diagnosis and treatment. Photoacoustic imaging (PAI) may change PCa management. This review examines PAI's principles, diagnostic role, and therapeutic guidance....
Photoacoustic imaging (PAI) offers non-invasive, high-resolution imaging with functional and molecular capabilities, enhancing prostate cancer detection and guiding therapies like biopsy and brachytherapy. Ongoing advancements aim to overcome depth limitations and enhance clinical utility through technological innovations and data analysis...
PROTACs targeting androgen receptor signaling: Potential therapeutic agents for castration-resistant prostate cancer
Source : https://pubmed.ncbi.nlm.nih.gov/38815882/
After the initial androgen deprivation therapy (ADT), part of the prostate cancer may continuously deteriorate into castration-resistant prostate cancer (CRPC). The majority of patients suffer from the localized illness at...
The development of PROTACs offers versatile options for degrading specific proteins, particularly androgen receptors (AR) in metastatic castration-resistant prostate cancer (mCRPC), showing promising clinical potential in treatment.