Axillary Response to Neoadjuvant Therapy in Node-Positive, Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer Patients: Predictors and Oncologic Outcomes - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35303178/
For patients with node-positive, ER+, HER2- breast cancer, a lower burden of disease at the time of diagnosis (stage II) is associated with a significantly higher axillary pCR, enabling those...
Conclusions: For patients with node-positive, ER , HER2- breast cancer, a lower burden of disease at the time of diagnosis (stage II) is associated with a significantly higher axillary pCR, enabling those patients to be spared axillary dissection. Further studies are necessary to define the role of genomic profiling in predicting axillary...
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Albert Dekker4yrvery few such patients have neo-adjuvant treatment
The Association Between Hormone Receptor Status and End-of-Life Care Among Patients With Metastatic Breast Cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35302550/
Background: In metastatic breast cancer (MBC), positive estrogen receptor (ER) and human epidermal growth factor receptor 2 (HER2) status allow for more long-term, sequential treatment options compared to ER-negative and...
Findings: Patients with ER-positive MBC had greater odds of receiving quality end-of-life care than those with ER-negative MBC. HER2 status was not associated with differences in the quality of end-of-life care.
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Albert Dekker4yryes they have longer disease course and longer planning
Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: updated efficacy and Ki-67 analysis from the monarchE study
Source : https://www.annalsofoncology.org/article/S0923-7534(22)00380-5/fulltext
Harbeck et al1 presented an update of the monarchE trial showing that the benefit of adjuvant abemaciclib is sustained beyond the two-year treatment period. They noted that benefit was observed...
Relevance: Given the added burden of treatment escalation in terms of toxicity and health expenditures, knowing the benefit of abemaciclib specifically in high-risk premenopausal women treated with modern risk-adapted endocrine treatment would help position the drug in clinical practice.
Life situations of Swedish women after mastectomy due to breast cancer: A qualitative study
Source : https://www.ejoncologynursing.com/article/S1462-3889(22)00024-2/fulltext
Breast cancer is a significant health issue all around the world and the most frequent type of cancer among Swedish women. The aim of this study was to explore and...
Conclusions:The women's body image limits their daily lives, and psychological distress reminds them of their disease. Reception of support from family and healthcare professionals and perception of positive life are important. Sometimes there is a lack of information and follow-up from healthcare professionals, who should be aware of the...
Ethiopian women's breast cancer self-examination practices and associated factors. A systematic review and meta-analysis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35272259/
This review and meta-analysis showed the ever and regular pooled prevalence of BCSE among Ethiopian women. More than one third of Ethiopian women ever practiced BCSE. We recommend that awareness...
Conclusion: This review and meta-analysis showed the ever and regular pooled prevalence of BCSE among Ethiopian women. More than one third of Ethiopian women ever practiced BCSE. We recommend that awareness creation should be perform in order to tackle the risk of breast cancer.