Adjuvant Olaparib for Germline BRCA Carriers With HER2-Negative Early Breast Cancer: Evidence and Controversies - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37210568/
In the OlympiA study, 1 year of adjuvant olaparib significantly extended invasive disease-free survival and overall survival. The benefit was consistent across subgroups, and this regimen is now recommended after...
Relevance: In this article, we review available data that could help guide treatment decisions for gBRCA1/2m carriers with high-risk, early-stage breast cancer.
Advances in the Management of Menopausal Symptoms, Fertility Preservation, and Bone Health for Women With Breast Cancer on Endocrine Therapy - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37229618/
In patients with hormone receptor-positive early-stage breast cancer, adjuvant endocrine treatment administered for up to 5-10 years after diagnosis significantly reduces the risk of recurrence and death. However, this benefit...
Conclusions/Relevance: This study aims to provide an updated overview of the available approaches for improving the QoL of patients with breast cancer receiving estrogen deprivation therapy, focusing on advances in the management of menopausal symptoms, including sexual dysfunction, fertility preservation, and bone health.
Improved Survival of Young Patients With Breast Cancer 40 Years and Younger at Diagnosis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37229627/
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Conclusion: We report survival rates of 89% at 5 years and 76% at 10 years with modern multidisciplinary management. Best results were seen in EBC: OS rates of 96% and 87% at 5 years and 10 years.
Dermoglandular advancement-rotation flap for conservative treatment of breast cancer - description of technique, objective and subjective assessments
Source : https://www.frontiersin.org/articles/10.3389/fonc.2023.1137924/full
Objectiveto describe and evaluate the dermoglandular advancement-rotation flap with no contralateral surgery as a technique for the conservative treatment of breast cancer when skin or a large proportion of gland...
Conclusion: Dermoglandular advancement-rotation flap technique with no contralateral surgery provides good symmetry when a large proportion of skin or gland requires resection on breast conservative cancer treatment.